Results 141 to 150 of about 1,455,736 (350)

Asking “How” and “Why” and “Under What Conditions” Questions: Using Critical Realism to Study Learning and Teaching

open access: yesTeaching & Learning Inquiry: The ISSOTL Journal
Research paradigms offer a way for scholars to design, communicate, and reflect on their research effectively. A paradigm encapsulates the researcher’s worldview, including the epistemology, ontology, and axiology of the research.
Janice Miller-Young
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Critical Thinking in Distance Education: The Challenges in a Decade (2016–2025) and the Role of Artificial Intelligence

open access: yesEducation Sciences
This qualitative study investigates how critical thinking is cultivated in postgraduate distance learning, focusing on two time points, 2016 and 2025, in the context of the Greek higher education system.
Evangelia Manousou
doaj   +1 more source

Knowledge society and collective intelligence. Factors in capacity-strengthening in African countries [PDF]

open access: yes, 2010
As we enter a world in which intellectual capital is fundamental, in which the central activities are no longer those aimed at producing and distributing goods but those that produce and distribute knowledge and information, the challenge for African ...
Anseur, Ouardia   +2 more
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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