Results 121 to 130 of about 14,468,283 (378)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Qu’est-ce que la critique dans la philosophie critique de la race ?

open access: yesAstérion
The article takes the notion of critique seriously in order to evaluate to what extent, according to what characterisations, under what conditions, and with what limits critical philosophy of race (CPR), which refers to critical race theory specifically ...
Magali Bessone
doaj   +1 more source

Critical Foundations of the Contextual Theory of Mind [PDF]

open access: yes, 2011
The contextual mind is found attested in various usages of the term complement, in the background of Kant. The difficulties of Kant's intuitionism are taken up through Quine, but referential opacity is resolved as semantic presence in lived context.
antiquari(at)vodamail(dot)co(dot)za, Mr S.A. Orwin O'Dowd
core  

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Analysing inequalities in tourism activities between local municipalities in the Eastern Cape Province of South Africa. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2016
Past official government policies on development under apartheid created unequal opportunities at different levels for the population in all the sectors of the South African economy.
Kofi Owusu Acheampong
doaj  

Extending Honneth’s Shift in Focus for Critical Theory [PDF]

open access: yes, 2016
Axel Honneth has called for a change of focus in Critical Theory "from the self-generated independence of systems to the damage and distortion of social relations of recognition." I argue that Honneth does not shift his methodological focus ...
Giles, Douglas
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Raízes sociais e psicodinâmicas do preconceito e suas implicações na educação inclusiva

open access: yesPsicologia Escolar e Educacional
Resumo Este artigo tem como objetivo discutir as raízes sociais e psicodinâmicas do preconceito e suas implicações na educação inclusiva. A teoria crítica da sociedade e a psicanálise são a base de sustentação deste artigo, de natureza eminentemente ...
Diana Villac Oliva
doaj   +1 more source

Rethinking the concept of effective participation: Are minorities similar to women? [PDF]

open access: yesJournal on Ethnopolitics and Minority Issues in Europe, 2010
The slogan ‘participation of minorities’ has long been a powerfulconcept in the vocabulary of human rights activists. Today it is alsoembraced by politicians and other actors promoting democraticdevelopments in European societies. Those who propagate the
Reetta Toivanen
doaj  

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