Results 111 to 120 of about 6,972,546 (297)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The assessment of critical thinking skills of gifted children before and after taking a critical thinking development course

open access: yes, 2021
The development of critical thinking is a fundamental task of the modern education system. However, practically, it turns out that a number of teachers are not competent enough in this area.
Gilmanshina S.   +3 more
core  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Correlational between: Biological literacy and metacognitive abilities with critical thinking in junior high school students

open access: yesJPBI (Jurnal Pendidikan Biologi Indonesia)
Facing the 21st century which is an educational challenge requires schools to be able to produce students who have biological literacy skills, metacognitive skills and critical thinking skills.
N. Najmah   +2 more
doaj   +1 more source

Learning critical thinking skills online: can precision teaching help? [PDF]

open access: yesEduc Technol Res Dev, 2023
Tan AJY   +3 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Artificial Intelligence-Generated Content Empowers College Students’ Critical Thinking Skills: What, How, and Why

open access: yesEducation Sciences
Despite the increasing number of studies indicating that generative artificial intelligence is conducive to cultivating college students’ critical thinking skills, research on the impact of college students’ use of generative artificial intelligence on ...
Weiping Zhang, Xinxin Liu
doaj   +1 more source

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