Results 191 to 200 of about 3,454 (266)

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Multifunctional Konjac Glucomannan Film Tuning by Gallic Acid Functionalization. [PDF]

Polymers (Basel)
Zasada L, Wekwejt M, Michalska-Sionkowska M, Michno A, Ronowska A, Fałkowska K, Dulok K, Kaczmarek-Szczepańska B.   +7 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Bleaching efficacy and enamel effects of tricalcium phosphate dentifrices containing charcoal or hydrogen peroxide. [PDF]

Braz Dent J
Santos GSD, Felix AF, Matos ICRT, Kury M, Cavalli V.   +4 more
europepmc   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Effect of Blue Covarine Toothpastes on Tooth Colour: A Randomised Crossover Study. [PDF]

Int Dent J
Zhang L, Joiner A, Gupta AK, Barili M, Platten S, McDonald MD, Luo W, Matheson JR.   +7 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Racism Counterfactuals in Health Research. [PDF]

J Racial Ethn Health Disparities
Bell CN, Blackson EA, Anderson A, Stojanovski K, Weller BE.   +4 more
europepmc   +1 more source

Gelation mechanism analysis of low-salt silver carp (<i>Hypophthalmichthys molitrix</i>) surimi enhancing by ultrasonication combined apple pectin, citrus pectin, or peach gum. [PDF]

Food Chem X
Si S, Huang D, Wang T, Sun Y, Qian Y, Liu X.   +5 more
europepmc   +1 more source

A sustainable spectrofluorimetric method for ivabradine quantification based on erythrosin B quenching with quantum mechanical modeling and Box-Behnken design optimization. [PDF]

RSC Adv
Alqahtani AS, Abduljabbar MH, Alnemari RM, Althobaiti MM, Aldawsari MF, Al-Mutairi AA, Serag A, Almalki AH.   +7 more
europepmc   +1 more source