Results 71 to 80 of about 15,936,821 (291)

Introduction : On the Margins

, 2023
Since its foundation as an academic field in the 1990s, critical race theory has developed enormously and has, among others, been supplemented by and (dis)integrated with critical whiteness studies.
Keskinen, Suvi, Tate, Shirley Anne, Andreassen, Rikke, Lundström, Catrin,   +3 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Myslinska, D. R. (2024) Law, Migration, and the Construction of Whiteness: Mobility Within the European Union

Australian and New Zealand Journal of European Studies
Myslinska’s Law, Migration, and the Construction of Whiteness is an important contribution to critical whiteness studies. Focusing on the EU’s commitment to freedom of movement, Myslinska illustrates how Central Eastern European (CEE) migrants are ...
Anna Christoforou
doaj   +1 more source

'Does he look like a Paki?' an exploration of 'whiteness', positionality and reflexivity in inter-racial sports research1851) [PDF]

, 2014
This article reflects on fieldwork with white and British Asian cricketers which explored the construction, maintenance and contestation of racialised identities in the sport of cricket.
Fletcher, T
core   +1 more source

Introduction : Identities

, 2023
Since its foundation as an academic field in the 1990s, critical race theory has developed enormously and has, among others, been supplemented by and (dis)integrated with critical whiteness studies.
Keskinen, Suvi, Tate, Shirley Anne, Andreassen, Rikke, Lundström, Catrin,   +3 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Introduction : Consumption

, 2023
Since its foundation as an academic field in the 1990s, critical race theory has developed enormously and has, among others, been supplemented by and (dis)integrated with critical whiteness studies.
Keskinen, Suvi,, Andreassen, Rikke,, Tate, Shirley Anne,, Lundström, Catrin,   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source