Results 61 to 70 of about 4,650,992 (309)

Geocomputing, New Technologies and Historical Analysis: Tools for a Changing Planet

open access: yesProceedings, 2019
Modern Earth Scientists need also to interact with other disciplines, apparently far from the Earth Sciences and Engineering. Disciplines related to history and philosophy of science are emblematic from this perspective.
Sebastiano Trevisani
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

How to determine critical Marangoni number in half floating zone convection

open access: yes, 1996
In the present paper, the coordinated measurements of the temperature profile inside the liquid bridge and the boundary variation of Free surface, in addition to other quantities, were obtained in the same time for the half floating zone convection.
刘芳   +3 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Principles and dynamics of the Critical Zone

open access: yes, 2015
Principles and Dynamics of the Critical Zone is an invaluable resource for undergraduate and graduate courses and an essential tool for researchers developing cutting-edge proposals.
Houser, Chris, Giardino, John R.
core  

Cave Dripwater Magnetic Minerals Record Seasonal Rainfall Variability: New Insights From a 5‐Years Field Monitoring in Central China

open access: yesGeochemistry, Geophysics, Geosystems
Stalagmites provide an invaluable archive at high‐resolution for paleoclimate studies. However, it is challenging to extract independent hydroclimate signals from stalagmites due to the scarcity of reliable hydrological proxies.
Taiheng Shi   +7 more
doaj   +1 more source

Mineral Weathering and Podzolization Control Acid Neutralization and Streamwater Chemistry Gradients in Upland Glaciated Catchments, Northeastern United States

open access: yesFrontiers in Earth Science, 2019
Headwater streams in the White Mountains, NH, United States have been shown to have downstream gradients of increasing pH and concentrations of base cations coupled with decreasing concentrations of aluminum.
Scott W. Bailey   +4 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Critical Zone 3: A Forum of Chinese and Western Knowledge

open access: yes, 2008
Critical Zone is an established series in cultural and literary studies jointly published by the Hong Kong University Press and Nanjing University Press. This is the third number.

core  

Examining Driver Behavior in Response to Work Zone Interventions: A Driving Simulator Study, 2010 [PDF]

open access: yes, 2010
Construction zones pose a significant threat to both workers and drivers causing numerous injuries and deaths each year. Innovations in work zone safety could reduce these numbers.

core  

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