Results 91 to 100 of about 50,351 (318)

The effect of burnable absorbers on criticality and reactivity coefficient of VVER-1000 assembly [PDF]

open access: yesNuclear Technology and Radiation Protection
Burnable absorbers play an important role in nuclear reactor safety and exploring their effect on the reactor core behavior is an important issue in the design and operation of the reactor core.
Zuhair   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Modelling the outer radiation belt as a complex system in a self-organised critical state [PDF]

open access: yes, 2005
The dynamic behaviour of the outer electron radiation belt makes this area of geo-space a candidate for the concept of self-organized criticality. It is shown here that frequency distributions of measured outer electron radiation belt data are well ...
Crosby, N. B.   +11 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Blackouts, risk, and fat-tailed distributions [PDF]

open access: yes
We analyze a 19-year time series of North American electric power transmission system blackouts. Contrary to previously reported results we find a fatter than exponential decay in the distribution of inter- occurrence times and evidence of seasonal ...
Ingve Simonsen, Rafal Weron
core  

Mixed-Criticality Systems with Partial Lockdown and Cache Reclamation Upon Mode Change [PDF]

open access: yes, 2017
29th Euromicro Conference on Real-Time Systems (ECRTS 2017), WiP. Dubrovnik, Croatia.In mixed-criticality multicore systems, the appropriate degree of isolation between applications of different criticalities is a primary objective.
Åkesson, Benny   +4 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A Memory Arbitration Scheme for Mixed-Criticality Multicore Platforms

open access: yes, 2014
In mixed-criticality systems, applications of different crit- icality levels share the same computing platform. To avoid spatial and temporal interference of the applications, the computing platform must implement measures for spatial and temporal ...
Cilku, Bekim, Puschner, Peter
core  

Modelling the tuned criticality in stick-slip friction during metal cutting [PDF]

open access: yes, 2015
Cutting is a ubiquitous process in nature and man-made systems. Here we demonstrate that, based on morphological patterns observed in experiments, the friction behaviour of metal cutting exhibits a criticality with cutting speed as a tuned parameter. The
Wang, Q (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China.   +4 more
core   +1 more source

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