Results 111 to 120 of about 50,351 (318)
Critical infrastructures protection research field is booming today because of the practical aspects and sometimes by taking in consideration its imminence character which should be addressed to it.
Badea Dorel +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Self-organising mechanism of neuronal avalanche criticality
A self-organising model is proposed to explain the criticality in cortical networks deduced from recent observations of neuronal avalanches. Prevailing understanding of self-organised criticality (SOC) dictates that conservation of energy is essential to
Juanico, Dr D.E.
core
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Criticality: its reflective utility within a technical and further education workplace context [PDF]
[Abstract]: This paper traces reflective practices through the lens of criticality as a commonality of mindset and action in relation to a teacher’s experience within a Technical and Further Education (TAFE) institute in Brisbane, Australia.
Tyler, Mark A.
core
ResumenPara la portada de este libro el autor ha elegido un dibujo muy atinado. Se trata de una ilustración de Saul Steinberg, arquitecto de formación e ilustrador de ofi cio, en el que se ve un cubo trazado en perspectiva axonométrica ligeramente ...
Fernando Quesada
doaj
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
A Hybrid Graph Hydrodynamic Method for Modelling Multiple Pipe Failure in Stormwater Networks
Modelling multiple pipe failure scenarios in stormwater networks is a challenging task due to the computational burden of conventional methods. In this context, this study proposes a hybrid graph hydrodynamic model (GHM) that combines the advantages of ...
Aun Dastgir +4 more
doaj +1 more source

