Results 101 to 110 of about 22,169,646 (299)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mixed Criticality Reward-Based Systems Using Resource Reservation

IEEE Access
Real-time systems mostly interact with the external world and each input operation must meet predetermined deadlines to be useful. However, in many real-time applications, a partial result is also acceptable. We developed a reward-based mixed criticality
Amjad Ali, Shah Zeb, Madallah Alruwaili, Asad Masood Khattak, Bashir Hayat, Ki-Il Kim   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Using Failure Mode, Effect and Criticality Analysis to improve safety in the cancer treatment prescription and administration process. [PDF]

J Pharm Policy Pract, 2023
Buja A, De Luca G, Ottolitri K, Marchi E, De Siena FP, Leone G, Maculan P, Bolzonella U, Caberlotto R, Cappella G, Grotto G, Lattavo G, Sforzi B, Venturato G, Saieva AM, Baldo V.   +15 more
europepmc   +1 more source

Blackouts, risk, and fat-tailed distributions [PDF]

We analyze a 19-year time series of North American electric power transmission system blackouts. Contrary to previously reported results we find a fatter than exponential decay in the distribution of inter- occurrence times and evidence of seasonal ...
Ingve Simonsen, Rafal Weron
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Failure mode effect and criticality analysis of ultrasound device by classification tracking. [PDF]

BMC Health Serv Res, 2022
Wang L, Li B, Hu B, Shen G, Zheng Y, Zheng Y.   +5 more
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A Data-Driven Global Load Case Analysis Method for Aircraft Structural Design

Actuators
Aircraft encounter complex ground and air scenarios during service, necessitating a comprehensive analysis of extensive global load cases during the design phase to ensure structural reliability and safety.
Yongbin Liu, Kaiyi Zheng, Xichang Liang, Qianqian Xin   +3 more
doaj   +1 more source