Results 91 to 100 of about 743,928 (343)
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Effect of Conjugated Hyperbilirubinemia on the Prognosis of Patients Hospitalized in Intensive Care Unit at Kariadi Hospital Semarang [PDF]
, 2010 Background: In critically-ill patients, liver dysfunction plays a significant role on patient's morbidity and mortality in the intensive care unit (ICU). Metabolic, hemodynamic and inflammatory factors also contribute in liver damage. Bilirubin is one of
Djallalluddin, D. (Djallalluddin) +3 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Pediatric Resuscitation: Evaluation of a Clinical Curriculum [PDF]
, 2003 Objective: To assess the impact of a 6-hour pediatric resuscitation curriculum on the comfort levels of resident physicians’ evaluation and treatment of critically ill pediatric patients. Methods: An evaluation instrument assessed resident comfort levels,
Brancati , DO, David S. +2 more
core
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Lateral positioning for critically ill adult patients
, 2008 We aim to assess the effect of the lateral position compared to other body positions on patient outcomes (mortality, morbidity and clinical adverse events during and following positioning) in critically ill adult patients.
Bucknall, Tracey K. +2 more
core +1 more source
Echocardiographic estimation of mean pulmonary artery pressure in critically ill patients [PDF]
, 2014 BACKGROUND: Indirect assessment of mean pulmonary arterial pressure (MPAP) may assist management of critically ill patients with pulmonary hypertension and right heart dysfunction.
Andrew D Bersten +2 more
core +2 more sources
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
The influence of patients infected with H1N1 influenza A virus on acute kidney injury
Linchuang shenzangbing zazhi, 2017 Objective To retrospectively review the clinical characteristics of severe and critically ill patients infected with 2009 pandemic influenza A(H1N1) virus,and analyze the factors associated with acute kidney injury(AKI) in HlNl-infected patients.Methods ...
LI Rui Ying-xin, LI Ying-xin
doaj
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source