Results 51 to 60 of about 223,947 (268)

Multiple Microbleeds: A Serious Neurological Manifestation in a Critically Ill COVID-19 Patient

Case Reports in Neurology, 2020
Coronavirus disease 2019 (COVID-19) is a viral illness caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There is worldwide emerging evidence of multisystem involvement including different neurological manifestations in ...
Khawaja Hassan Haroon, Satya Narayana Patro, Suhail Hussain, AbdulAziz Zafar, Ahmad Muhammad   +4 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Impact on the work of clinical pharmacist at the pharmacotherapy management of critically ill patient: Local experience in a clinical hospital [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2018
Context: The complexity in critical patient management and polypharmacy, raise the need for support from a clinical pharmacist to optimize drug therapies.
Jorge S. Amador, Ruben A. Hernández, Cristian M. Gutiérrez, José C. Plaza-Plaza   +3 more
doaj  

The Relationship between the Physical Restraints and Physiological Parameters among Critically Ill Patients [PDF]

Egyptian Journal of Health Care
Background: Most of critically ill patients are mechanically ventilated, attached to multiple invasive devices, suffering of the disease, and the particularity of treatment. Physical restraints are commonly used in intensive care units to reduce the risk
Hala Lotfy Mostafa, Hanan Sobeih Sobeih, Reham Adel Ebada   +2 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Enteral nutrition discontinuation and outcomes in general critically ill patients

Clinics, 2013
OBJECTIVE: To determine the relationship between enteral nutrition discontinuation and outcome in general critically ill patients. MATERIALS AND METHODS: All patients admitted to a mixed intensive care unit in a tertiary care hospital from May-August ...
Marco Antonio Silva, Saionara da Graca Freitas dos Santos, Cristiane Damiani Tomasi, Gabrielle da Luz, Marcos Marques da Silva Paula, Felipe Dal Pizzol, Cristiane Ritter   +6 more
doaj  

A Successful Experience of Individualized Vancomycin Dosing in Critically Ill Patients by Using a Loading Dose and Maintenance Dose

Pharmaceuticals
Background/Objective: Vancomycin, a hydrophilic glycopeptide antibiotic with bactericidal activity against Gram-positive microorganisms, is one of the most commonly used antibiotics un the intensive care unit (ICU).
Jorge S. Amador, Álvaro Vega, Patricio Araos, Luis A. Quiñones, Cristián A. Amador   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Nurses’ Perception Regarding Barriers of Early Mobilization among Critically Ill Patients [PDF]

Egyptian Journal of Health Care
Background: Early mobilization among critically ill patients is a safe and effective intervention that can have a significant impact on functional outcomes and prevent immobility complications. Aim: This study aimed to assess nurses’ perception regarding
Alaa Mohamed Souliman Mohamed, Amany Mohamed Safwat, Samar Faltas Marzouk   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source