Results 61 to 70 of about 223,947 (268)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Psychlological Nursing on the Accompaniers and Family Relatives of Critically ⅢPatients

Huli yanjiu, 1995
By using practicable examples,the author emphasized the necessity and importance of giving the psychological nursing to the accompaniers and family relatives of critically ill patients so as to offer them necessary psychological guide and consulting ...
汪建英
doaj  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Magnesium in the Critically Ill Patient [PDF]

Veterinary Clinics of North America: Small Animal Practice
Magnesium is an electrolyte essential for life and plays a crucial role in several biochemical and physiologic processes in the body. Dysmagnesemia, defined as the presence of either hypomagnesemia or hypermagnesemia, is common in critically ill patients and is associated with prolonged hospitalization and increased mortality. This article reviews: (1)
Llewellyn, Efa, Cutler, Simone
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nurses' Performance Regarding Acquired Sleep Deprivation among Critically Ill Patients [PDF]

Helwan International Journal for Nursing Research and Practice
Critically ill patients commonly experience poor sleep quality and sleep deprivation. Aim: assess nurses’ performance regarding acquired sleep deprivation among critically ill patients. Design: Descriptive exploratory research design.
Nora Gamal Mohamed
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Effect of Natural Probiotics on the Enterally Fed Critically Ill Patients’ Outcomes [PDF]

Alexandria Scientific Nursing Journal
Background: The management of critical illness in the contemporary intensive care units(ICUs) creates an adverse environment in the gut of the critically ill and alters themicrobiome.
Nagwa Ahmed Reda, Nermeen Farouk Abdel All Elsayed, Mohamed Mostafa Abd Elsalam Megahed, Eman Ali   +3 more
doaj   +1 more source

Hypertension in the Critically Ill Patient

Critical Care and Resuscitation, 2003
To review the management of persistent hypertension and hypertensive crisis in the critically ill patient.A review of articles reported on hypertension and the critically ill patient.Hypertension is defined as a basal systolic blood pressure of greater than 140 mmHg or diastolic blood pressure of greater than 90 mmHg (MAP > 105 mmHg), irrespective of ...
R, Santhi, Lindsay I G, Worthley
openaire   +2 more sources