Results 111 to 120 of about 429,654 (310)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 1906 05 janvier 19061906/01/05 (A12,N232)-1906/12/20 (A12,N242).Note : Titre cette année : La Critique et Bulletin des ...
Association artistique et littéraire de "La Critique". Auteur du texte
core
LE THÉME DU VOYAGE DANS LA LITTÉRATURE FRANÇAISE DES LUMIÈRES [PDF]
Studii si Cercetari Filologice: Seria Limbi Romanice, 2011 Le thème du voyage représente un cadre généreux de manifestation littéraire de la pensée des Lumières. Si voyage il y a tant chez Montesquieu, que chez Voltaire et Diderot, il n’est pas un but en soi, mais un prétexte pour des développements critiques ...
Alexandrina MUSTATEA
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sociologies, 2015 Pragmatic sociology long considered that it had nothing to say about power games. One of its rules of method required focusing on the actors themselves when undertaking to reveal, through work on controversies and trials, the figures of power and ...
Francis Chateauraynaud
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
La critique architecturale, objet de recherche
, 2009 International audienceDefining, architectural criticism – demarcating its area, determining it or its objects (technology, program, form, modes of construction) and identifying its tasks – is a chronic matter of concern in a large number of debates and ...
Hélène Jannière, Janniere, Helene
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source