Results 101 to 110 of about 19,663 (194)
Overall Survival as per exposure to Crizotinib.
, 2016 Overall Survival as per exposure to Crizotinib.
Vipul Doshi (3123906) +12 more
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Cell Death and DiseaseCrizotinib carries an FDA hepatotoxicity warning, yet analysis of the FAERS database suggests that the severity of its hepatotoxicity risks, including progression to hepatitis and liver failure, might be underreported.
Lin Guo +14 more
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Neoadjuvant crizotinib in advanced inflammatory myofibroblastic tumour with ALK gene rearrangement
, 2015 Background\ud \ud Inflammatory myofibroblastic tumours (IMTs) are rare sarcomas that were first described in the lung. They are composed of myofibroblastic mesenchymal spindle cells accompanied by an inflammatory infiltrate of plasma cells.
Hennessy, Bryan +10 more
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Crizotinib in ALK-positive lung cancer
, 2012 Comment on : Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study. [Lancet Oncol.
Girard, Nicolas
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Current OncologyWe aimed to evaluate the therapeutic potential of crizotinib, a broad-spectrum tyrosine kinase inhibitor against bladder cancer (BC) cells, based on a three-dimensional (3D) cell culture system.
Byeongdo Song +4 more
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Crizotinib attenuates bleomycin-induced pulmonary fibrosis via regulating fibroblast activation
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic interstitial lung disease. Crizotinib is an oral tyrosine kinase inhibitor (TKI), which has been widely used in the treatment of non-small cell lung cancer (NSCLC ...
Shi, Yujie +6 more
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Supplementary Figures 1-5 from Crizotinib Induces PUMA-Dependent Apoptosis in Colon Cancer Cells
, 2013 PDF file - 549 KB, Figure S1: Expression of Bcl-2 family proteins before and after crizotinib treatment; Figure S2: Crizotinib induces PUMA-dependent apoptosis; Figure S3: Crizotinib induces p53-dependent induction of PUMA and apoptosis in colon cancer ...
Kan He (139670) +3 more
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Clinical Research of Crizotinib in Advanced Non-small Cell Lung Cancer
Chinese Journal of Lung Cancer, 2013 At present, in the treatment of non-small cell lung cancer (NSCLC), targeted therapy has an important status. After epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKIs), crizotinib targeted at EML4-ALK fusion gene becomes a significant ...
Haibo ZHU, Xiaoyu XU, Ling WANG
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Crizotinib in Advanced, Chemoresistant Anaplastic Lymphoma Kinase–Positive Lymphoma Patients
, 2014 Anaplastic lymphoma kinase (ALK)-positive lymphomas respond to chemotherapy, but relapses, which bear a poor prognosis, occur. Crizotinib inhibits ALK in vitro and in vivo and was administered as monotherapy to 11 ALK+ lymphoma patients who were ...
Michael H. King +41 more
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Pharmacogenomics and Personalized Medicine, 2015 Hazem El-Osta,1 Rodney Shackelford2 1Department of Medicine, 2Department of Pathology, Feist-Weiller Cancer Center, Louisiana State University Health Science Center-Shreveport, Shreveport, LA, USA Abstract: The fusion of echinoderm microtubule ...
El-Osta H, Shackelford R
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