Results 151 to 160 of about 10,538,494 (333)

Crohn's disease [PDF]

, 2013
Crohn's disease The Bachelor study summarizes the present knowledge of inflammatory diseases, which attack the digestive system. The Crohn's disease is classified as idiopathic or nonspecific intestine inflammations, since its cause is still not known ...
Štorkánová, Hana
core  

Accuracy and cost of diagnostic strategies for patients with suspected Crohn's disease

, 2014
Objective: To evaluate accuracy and cost of non-invasive diagnostic strategies including magnetic resonance imaging, intestinal ultrasonography, ileocolonoscopy and video-capsule endoscopy in suspected Crohn's disease.
P. Duca, E. Bolzoni, A. B. Friedman, G. Maconi, A. Giussani   +4 more
core   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Crohn's Disease [PDF]

Postgraduate Medical Journal, 1949
openaire   +3 more sources

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

A family study of asymptomatic small bowel Crohn's disease

, 2014
Background: Discrepancies between severity of lesions and symptoms may be observed in Crohn's disease. We prospectively assessed whether Crohn's disease may be diagnosed among asymptomatic relatives of patients, using Small Bowel Contrast Ultrasonography.
Calabrese E., Zorzi F., Pallone F., Petruzziello C., Ciccacci C., Lolli E., Borgiani P., Condino G., Capanna A., Onali S., Biancone L.   +10 more
core   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach

Gut, 2005
C. Manichanh, L. Rigottier-Gois, Elian Bonnaud, K. Gloux, É. Pelletier, L. Frangeul, R. Nalin, C. Jarrin, P. Chardon, P. Marteau, Joaquim Roca, J. Doré   +11 more
semanticscholar   +1 more source

Early life exposures and risk for inflammatory bowel disease: a nested case-control study in Quebec, Canada

, 2023
Background Early childhood is an important period for the establishment of gut microbiota. Most early life risks or protective factors for inflammatory bowel disease are likely to act through an effect on the gut microbiota.
Jantchou, Prévost, Nicolau, Belinda, Rousseau, Marie-Claude, Madathil, Sreenath A., Benedetti, Andrea, Fantodji, Canisius   +5 more
core