Results 261 to 270 of about 181,938 (338)

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Small Bowel Adenocarcinoma Masquerading as Crohn's Disease. [PDF]

Cureus
Kim SY, Wiggins B, Ramirez D, Minaudo M.
europepmc   +1 more source

Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 474-485, March 2025.
Abstract Mirikizumab is a p19‐directed anti‐interleukin‐23 antibody approved for the treatment of adults with moderate‐to‐severe ulcerative colitis (UC). Here, we report the first data of mirikizumab pharmacokinetics (PK) and exposure–response (E/R) relationships in pediatric participants (aged 2 to <18 years weighing >10 kg) with moderate‐to‐severe UC
Yuki Otani, Laiyi Chua, Wendy J. Komocsar, Amy Larkin, Jordan Johns, Xin Zhang   +5 more
wiley   +1 more source

Perianal Crohn's Disease in Inflammatory Bowel Disease: Diagnosis, Assessment and Treatment. [PDF]

Life (Basel)
Faggiani I, Villaseca IL, D'Amico F, Furfaro F, Zilli A, Massironi S, Parigi TL, Solitano V, Cicerone C, Peyrin-Biroulet L, Danese S, Allocca M.   +11 more
europepmc   +1 more source

Comparison of the Safety and Efficacy of Ustekinumab and Vedolizumab in Patients with Crohn’s Disease: A Systematic Review and Meta-Analysis of Propensity Score Matched Cohort Studies [PDF]

Andrea Pasta, Francesco Calabrese, Elisa Marabotto, Manuele Furnari, Maria Giulia Demarzo, Raffaele Pellegrino, Antonietta Gerarda Gravina, Alessandro Federico, Edoardo G. Giannini, Giorgia Bodini   +9 more
openalex   +1 more source

Appendiceal Crohn's Disease Manifesting as Appendiceal Malignancy: A Case Report and Review of the Literature

The Kaohsiung Journal of Medical Sciences, EarlyView.
Ming‐Jung Meng, Tai‐Di Chen, Puo‐Hsien Le, Chia‐Jung Kuo   +3 more
wiley   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

Small, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi, Benedikt Kronast, Jennifer Munkert, Lorenzo Sana, Marcus Koch, Heike Danzer, Sirka Dormeyer, Shuhan Jiang, Fabian Herrmann, Matthias Weiler, Anna Kashkanova, Vahid Sandoghdar, Mario M. Zaiss, Gregor Fuhrmann   +13 more
wiley   +1 more source

Genomic analysis unlocks the potential of denosumab as a targeted therapy for Crohn's disease. [PDF]

Sci Rep
Pranata R, Ratnasari N, Bayupurnama P, Indrarti F, Aulia N, Rahmawati H, Adikusuma W, Mugiyanto E, Irham LM, Gunarto C, Alya SS, Hadi VF, Sentosa GC, Wahyuningsih AT, Lin CF, Satria RD.   +15 more
europepmc   +1 more source

Associations between early life exposure to parvovirus and antibiotic treatment and the occurrence and severity of later chronic enteropathy in dogs

Veterinary Record, EarlyView.
Abstract Background Canine parvovirus (CPV) infection is reportedly associated with chronic enteropathy (CE), but infected puppies are often treated with antibiotics, which may also promote CE. This study aims to compare the presence and severity of CE among dogs that were CPV‐infected, treated with antibiotics or healthy during puppyhood.
Sharon Kuzi, Neta Goldstein, Gila Sutton, Gilad Segev   +3 more
wiley   +1 more source

JAK Inhibitor and Crohn's Disease. [PDF]

Biomedicines
Xu M, Wang S, Xu S, Gong R.
europepmc   +1 more source