Results 261 to 270 of about 97,874 (310)

Clinical use of Infliximab in Crohn’s disease: the Edinburgh experience

, 2001
Ian Arnott, Daniel McDonald, Anna Williams, Subrata Ghosh   +3 more
openalex   +1 more source

The Understudied Landscape of Hidradenitis Suppurativa in Asian Skin of Colour Populations

JEADV Clinical Practice, EarlyView.
Anju George
wiley   +1 more source

Epidemiology and the cost burden of hospitalized pediatric‐onset inflammatory bowel disease in China: A national database study

Pediatric Investigation, EarlyView.
This study provides insights into the clinical characteristics and cost burden of pediatric‐onset inflammatory bowel disease (PIBD) and very early onset IBD (VEO‐IBD) in China. Hospitalizations for PIBD, particularly Crohn's disease, are increasing. Guidelines and health insurance policies can help mitigate the cost burden.
Xiaolu Nie, Jing Li, Hui Xu, Fang Hu, Xiaolin Ye, Mengmeng Yu, Guoshuang Feng, Yueping Zeng, Xin Ni, Jie Wu, Xiaoxia Peng, the Futang Research Center of Pediatric Development (FRCPD)   +11 more
wiley   +1 more source

Longstanding Perianal Ulcers

JEADV Clinical Practice, EarlyView.
Narachai Julanon, Thanaphon Anutraungkool, Sirawich Jessadapattarakul, Vincent Piguet   +3 more
wiley   +1 more source

Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 474-485, March 2025.
Abstract Mirikizumab is a p19‐directed anti‐interleukin‐23 antibody approved for the treatment of adults with moderate‐to‐severe ulcerative colitis (UC). Here, we report the first data of mirikizumab pharmacokinetics (PK) and exposure–response (E/R) relationships in pediatric participants (aged 2 to <18 years weighing >10 kg) with moderate‐to‐severe UC
Yuki Otani, Laiyi Chua, Wendy J. Komocsar, Amy Larkin, Jordan Johns, Xin Zhang   +5 more
wiley   +1 more source

Interleukin‐1 receptor type II and inflammatory bowel disease: A Mendelian randomization study

Rheumatology &Autoimmunity, EarlyView.
This Mendelian Randomization study investigated the association between interleukin‐1 receptor type II (IL‐1RII) and inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC) by utilizing the genome‐wide association studies summary statistics.
Qifan Feng, Nan Li, Yawen Lu, Yinqi Long, Yaru Zhang, Kexin Ma, Shengxiao Zhang, Caihong Wang   +7 more
wiley   +1 more source

Micro‐ and nanomotors in biomedical applications

Responsive Materials, EarlyView.
Micro‐ and nanomotors (MNMs), as autonomous devices converting chemical or external energy into mechanical propulsion, have emerged as transformative drug delivery platforms in biomedicine. This review systematically outlines the design principles governing MNMs' propulsion and operation, highlights the applications of MNMs in disease treatment, and ...
Xiangyu Meng, Yuqi Tang, Quan Li
wiley   +1 more source

Decreased multidrug resistance protein 1 and increased platelet activation in obstructive sleep apnea syndrome

Sleep Research, EarlyView.
There was a positive correlation between apnea/hypopnea index (AHI) index and platelet aggregation and a negative correlation between CD42b and multidrug resistance protein 1 (MRP1). Platelet activation was high while MRP1 expression was low in severe obstructive sleep apnea syndrome (OSAS) independent of smoking, age, and gender.
Cigdem Bayram Gurel, Engin Korkmaz, Suzan Adin Cinar, Gülsel Ayaz, Bulent Tutluoglu, Gunnur Deniz, Arzuhan Koç, Turgut Ulutin, Gonul Kanigur   +8 more
wiley   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, Volume 21, Issue 29, July 24, 2025.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Seroreactivity againstSaccharomyces cerevisiaein patients with Crohn’s disease and celiac disease

, 2003
Zsolt Barta
openalex   +1 more source