Results 301 to 310 of about 180,947 (337)

Tissue-specific and circulatory immune signatures of mucosal inflammation in Crohn’s disease

Ramirez-Navarro L, Jones G, Alegbe T, Harris BT, Strickland M, Ghouraba M, Ostermayer J, Wana N, Hu MX, Skelton J, Garri W, Brezina B, Caballes CQ, Leonard S, Iyer V, McIntyre RE, Parkes M, Martin CC, Anderson CA, Raine T.   +19 more
europepmc   +1 more source

The Potential of High-Density Lipoprotein as a Predictive Biomarker for Infliximab Efficacy in Crohn's Disease. [PDF]

J Inflamm Res
Tang K, Peng Z, Xu D, Li Y, Liu X, Lian G, Peng Y.   +6 more
europepmc   +1 more source

Pharmacological management of upper gastrointestinal Crohn's disease: a systematic review. [PDF]

J Crohns Colitis
Chatto M, Alaskar D, Ma C, Yuan Y, Vuyyuru SK, Bessissow T, Narula N, Danese S, Peyrin-Biroulet L, Singh S, Jairath V, Sedano R.   +11 more
europepmc   +1 more source

Luteolin Inhibits NLRP3 Inflammasome Activation to Ameliorate DSS‐Induced Colitis by Regulating AMPK Signalling

Cell Proliferation, EarlyView.
Luteolin alleviates DSS‐induced ulcerative colitis in mice by targeting the NLRP3 inflammasome, as it shows no effect in NLRP3‐/‐ mice. It inhibits NLRP3 activation and IL‐1β secretion in macrophages by reducing ROS, mtROS and calcium levels via AMPK binding and signalling. Metabolomic changes suggest lipid metabolism involvement. Luteolin represents a
Lianxiang Luo, Fangfang Huang, Guixuan Fang, Yiming Sun, Liyan Deng, Yinglin Liao, Xinming Chen, Zhuosi Chen, Xinxun Lin   +8 more
wiley   +1 more source

AMSC‐sEVs Ameliorated Crohn's Disease by Inhibiting Macrophage‐Myofibroblast Transition Through the Delivery of MFGE8

Cell Proliferation, EarlyView.
Our study demonstrated that TGF‐β1 activated MAPK signalling pathway and promoted the MMT and secretion of CCL17 under CD‐associated intestinal inflammatory conditions. AMSC‐sEVs can deliver MFGE8, which inhibits MMT and CCL17‐mediated Treg recruitment by suppressing the MAPK signalling pathway, thereby alleviating intestinal fibrosis.
Minghao Xie, Qiang Liu, Zhizhong Xiong, Jian Li, Ruiri Jin, Lei Lian, Zhengrong Li   +6 more
wiley   +1 more source

An unforgettable diagnostic journey: multimodal evaluation of jejunal diverticulitis mimicking Crohn's disease. [PDF]

Endoscopy
Abdulrasak M, Makitan M, Wurm Johansson G, Nemeth A, Koulaouzidis A, Toth E.   +5 more
europepmc   +1 more source

Cutaneous non‐tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Cutaneous non‐tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24‐year‐period. Patients and Methods 73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000 ...
Luisa Bopp, Nicolai Deresz, Henning Klapproth, Isabelle Suárez, Jonathan Jantsch, Mario Fabri, Esther von Stebut   +6 more
wiley   +1 more source

Risk Factors for Chronic Kidney Disease in Patients With Crohn's Disease. [PDF]

Inflamm Bowel Dis
Rodriguez A, Quintero MA, Hazime H, Killian R, Ducasa GM, Faust KM, Abreu MT.   +6 more
europepmc   +1 more source