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Nature Reviews Disease Primers, 2020
Crohn's disease is an inflammatory bowel disease that is characterized by chronic inflammation of any part of the gastrointestinal tract, has a progressive and destructive course and is increasing in incidence worldwide. Several factors have been implicated in the cause of Crohn's disease, including a dysregulated immune system, an altered microbiota ...
Giulia Roda +2 more
exaly +9 more sources
Crohn's disease is an inflammatory bowel disease that is characterized by chronic inflammation of any part of the gastrointestinal tract, has a progressive and destructive course and is increasing in incidence worldwide. Several factors have been implicated in the cause of Crohn's disease, including a dysregulated immune system, an altered microbiota ...
Giulia Roda +2 more
exaly +9 more sources
The Lancet, 2017
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract, with increasing incidence worldwide. Crohn's disease might result from a complex interplay between genetic susceptibility, environmental factors, and altered gut microbiota, leading to dysregulated innate and adaptive immune responses.
Torres, Joana +3 more
openaire +3 more sources
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract, with increasing incidence worldwide. Crohn's disease might result from a complex interplay between genetic susceptibility, environmental factors, and altered gut microbiota, leading to dysregulated innate and adaptive immune responses.
Torres, Joana +3 more
openaire +3 more sources
Location is important: differentiation between ileal and colonic Crohn’s disease
Nature Reviews Gastroenterology and Hepatology, 2021Raja Atreya +2 more
exaly +2 more sources
BMJ, 2014
#### The bottom line Crohn’s disease is a chronic inflammatory disorder that can affect any part of the gastrointestinal tract. Although the disease most commonly presents at a young age, it can affect people of all ages. Patients often present with persistent diarrhoea, abdominal pain, and weight loss. Crohn’s disease has a global impact on patients’
R. Kalla +3 more
openaire +4 more sources
#### The bottom line Crohn’s disease is a chronic inflammatory disorder that can affect any part of the gastrointestinal tract. Although the disease most commonly presents at a young age, it can affect people of all ages. Patients often present with persistent diarrhoea, abdominal pain, and weight loss. Crohn’s disease has a global impact on patients’
R. Kalla +3 more
openaire +4 more sources
Current Problems in Surgery, 1993
The clinical and pathological description of Crohn’s disease (CD) in 1932 described inflammation of the terminal ileum (1). It was not until 1959, 100 yr after Samuel Wilks described ulcerative colitis (UC), that variants of CD were recognized to potentially, or exclusively, involve the colon (2).
G E, Block +4 more
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The clinical and pathological description of Crohn’s disease (CD) in 1932 described inflammation of the terminal ileum (1). It was not until 1959, 100 yr after Samuel Wilks described ulcerative colitis (UC), that variants of CD were recognized to potentially, or exclusively, involve the colon (2).
G E, Block +4 more
openaire +2 more sources
Medicina Clínica (English Edition), 2018
Crohn's disease is a chronic inflammatory bowel disease of unknown etiology associated with an impaired immune response, with periods of activity and remission. It is characterised by patchy and transmural lesions which can affect the entire gastrointestinal tract, from the mouth to the anus. The most frequent symptoms are abdominal pain and diarrhoea,
María Pilar, Ballester Ferré +2 more
openaire +4 more sources
Crohn's disease is a chronic inflammatory bowel disease of unknown etiology associated with an impaired immune response, with periods of activity and remission. It is characterised by patchy and transmural lesions which can affect the entire gastrointestinal tract, from the mouth to the anus. The most frequent symptoms are abdominal pain and diarrhoea,
María Pilar, Ballester Ferré +2 more
openaire +4 more sources
Colorectal cancer in Crohn's disease: a Scandinavian population-based cohort study.
The Lancet Gastroenterology and Hepatology, 2020BACKGROUND Crohn's disease is a risk factor for colorectal cancer (CRC). However, available studies reflect older treatment and surveillance strategies, and most have assessed risks for incident CRC without taking surveillance and lead-time bias into ...
O. Olén +8 more
semanticscholar +1 more source
The Lancet
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract that might lead to progressive bowel damage and disability. The exact cause of Crohn's disease is unknown, but evidence points towards multifactorial events causing dysregulation of the innate immune system in genetically susceptible people.
Dolinger, Michael +2 more
openaire +3 more sources
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract that might lead to progressive bowel damage and disability. The exact cause of Crohn's disease is unknown, but evidence points towards multifactorial events causing dysregulation of the innate immune system in genetically susceptible people.
Dolinger, Michael +2 more
openaire +3 more sources
The Indian Journal of Pediatrics, 2006
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract and is an important cause of morbidity in children and adolescents. In India Crohn's disease (CD) was considered a rare disease, however, during the last 10 years CD in adults is being reported from several centers especially in Southern India.
Malathi, Sathiyasekaran, So, Shivbalan
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Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract and is an important cause of morbidity in children and adolescents. In India Crohn's disease (CD) was considered a rare disease, however, during the last 10 years CD in adults is being reported from several centers especially in Southern India.
Malathi, Sathiyasekaran, So, Shivbalan
openaire +2 more sources