Results 191 to 200 of about 1,146,385 (319)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Spatial distribution of entomopathogenic nematodes and their relationship with soil chemical attributes in tropical agroecosystems. [PDF]

Environ Monit Assess
Souza N, Andaló V, Indjai LR, Martins GD, de Faria LS, de Assis GA.   +5 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Semi-Natural Habitats Buffer the Effects of Crop Diversification on Arthropod Pest Control Services in Agricultural Landscapes. [PDF]

Ecol Lett
Perrot T, Beaumelle L, Thomine E, Tricault Y, Desneux N, Albrecht M, Batáry P, Bianchi F, Birkhofer K, Bosem Baillod A, Chaplin-Kramer R, Cortesero AM, Costamagna AC, Diekötter T, Ekroos J, Entling MH, Gagic V, Groves R, Huseth A, Jaworski C, Kaiser M, Karp DS, Krauss J, Lavandero B, Le Ralec A, Lu Y, Martin EA, Mitchell M, Molina GAR, Palmu E, Perovic DJ, Ragsdale D, Redlich S, Samaranayake I, Saulais J, Schellhorn NA, Steffan-Dewenter I, Sutter L, Tscharntke T, Tschumi M, Rusch A.   +40 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Farmland and Cropping Pattern Dynamics in Myanmar: Implications for Food Security and Sustainable Agriculture. [PDF]

Foods
Naing SY, Zhen L, Xiao Y, Liu X, Wen X.
europepmc   +1 more source

Crop of contention [PDF]

Frontiers in Ecology and the Environment, 2003
openaire   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Agrohydrological analysis of waterlogging impacts and mitigation in Ethiopia. [PDF]

NPJ Sustain Agric
Wakjira MT, Molnar P, Bartholomeus R, Erkossa T, Descheemaeker K.   +4 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source