Results 61 to 70 of about 1,553,190 (313)
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Abscisic Acid and Abiotic Stress Tolerance in Crop Plants
Frontiers in Plant Science, 2016 Abiotic stress is a primary threat to fulfill the demand of agricultural production to feed the world in coming decades. Plants reduce growth and development process during stress conditions, which ultimately affect the yield.
S. Sah, K. R. Reddy, Jiaxu Li
semanticscholar +1 more source
Distribution of Crops and Cropping Patterns in Bangladesh
Bangladesh Rice Journal, 2018 Agricultural land use and distribution of cultivated crops expressed in cropping pattern (CP) constitute the base for increasing produtivity. An in-depth study was conducted on the existing CPs of Bangladesh in each and every upazila (sub-districts) using semi structured questionnaire and data validation by the stakeholder consultation workshop ...
MA Ali +6 more
openaire +2 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban +12 more
wiley +1 more source
Crops and Cropping Systems in Dinajpur Region
Bangladesh Rice Journal, 2018 The development of agricultural planning largely depends on the reliable and comprehensive statistics of the existing cropping patterns, cropping intensity and crop diversity of a particular area, which will provide a guideline to the policy makers, researchers, extensionists and development workers.
BJ Shirazy +3 more
openaire +2 more sources
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Experimental Agriculture, 1965 SummaryThe analysis of radiation climate is a central problem of agricultural meteorology because rates of photosynthesis depend on the receipt of visible light and rates of transpiration depend on the net exchange of radiation by a crop canopy. Both short-wave (solar) and long-wave (terrestrial) radiation are correlated with cloud amount, and in south-
openaire +2 more sources