Results 51 to 60 of about 74,098 (264)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Understanding the Temporal Dynamics of Coherence and Backscattering Using Sentinel-1 Imagery for Crop-Type Mapping

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
This study investigates the application of coherence and backscattering, derived from time-series Sentinel-1 synthetic aperture radar imagery of a crop season (18 scenes with a 12-day revisit cycle), for crop growth monitoring and classification in the ...
Qinxin Zhao, Qinghua Xie, Xing Peng, Kunyu Lai, Jinfei Wang, Haiqiang Fu, Jianjun Zhu, Yang Song   +7 more
doaj   +1 more source

Crop Classification Based on a Novel Feature Filtering and Enhancement Method

Remote Sensing, 2019
Vegetation indices, such as the normalized difference vegetation index (NDVI) or enhanced vegetation index (EVI) derived from remote sensing images, are widely used for crop classification.
Limin Wang, Qinghan Dong, Lingbo Yang, Jianmeng Gao, Jia Liu   +4 more
doaj   +1 more source

Automatic Crop Classification Based on Optimized Spectral and Textural Indexes Considering Spatial Heterogeneity

Remote Sensing, 2023
Crop recognition with high accuracy at a large scale is hampered by the spatial heterogeneity of crop growth characteristics under the complex influence of environmental conditions.
Xiaomi Wang, Jiuhong Liu, Peng Peng, Yiyun Chen, Shan He, Kang Yang   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Mapping Main Grain Crops and Change Analysis in the West Liaohe River Basin with Limited Samples Based on Google Earth Engine

Remote Sensing, 2023
It is an important issue to explore achieving high accuracy long-term crop classification with limited historical samples. The West Liaohe River Basin (WLRB) serves as a vital agro-pastoral ecotone of Northern China, which experiences significant changes
Zhenxing Wang, Dong Liu, Min Wang
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Canopy-Level Spectral Variation and Classification of Diverse Crop Species with Fine Spatial Resolution Imaging Spectroscopy

Remote Sensing
With the increasing availability and volume of remote sensing data, imaging spectroscopy is an expanding tool for agricultural studies. One of the fundamental applications in agricultural research is crop mapping and classification. Previous studies have
Jie Dai, Marcel König, Elahe Jamalinia, Kelly L. Hondula, Nicholas R. Vaughn, Joseph Heckler, Gregory P. Asner   +6 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source