Results 31 to 40 of about 63,467 (267)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Effects of Saline Irrigation Water Applications on Evapotranspiration Partitioning and Crop Coefficient of Tomato Grown in Mediterranean-Type Greenhouses

open access: yesAgronomy
Accurate information regarding crop evapotranspiration (ETc) and its components is essential for proper water management. Salinity has become increasingly serious in many parts of the world, affecting the use of saline water in irrigation for various ...
Gulcin Ece Aslan   +5 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Relationship between crop coefficient and soil evaporation in forage grassland under sprinkler irrigation in Lhasa Valley

open access: yesGuan'gai paishui xuebao
【Objective】 Crop coefficient and soil evaporation are two important parameters for calculating evapotranspiration in terrestrial ecosystems but they are dependent on many factors.
XU Bing   +4 more
doaj   +1 more source

Effects of Subsurface Water Retention Technology on Crop Coefficient and Crop Evapotranspiration of Eggplant

open access: yesJournal of Engineering, 2018
In this paper, the effects of subsurface water retention technology (SWRT) on crop coefficient (kc) and crop evapotranspiration (ETc) of eggplant were investigated in sandy loam soil.
Sabah Anwer Almasraf, Ahmed Hatif Salim
doaj   +1 more source

SURFACE ENERGY BALANCE SYSTEM (SEBS) AND SATELLITE DATA FOR MONITORING WATER CONSUMPTION OF IRRIGATED SUGARCANE [PDF]

open access: yesEngenharia Agrícola, 2016
The objective of this research was to evaluate the water consumption of irrigated sugarcane areas using the Surface Energy Balance System (SEBS) driven by products derived from Meteosat Second Generation (MSG), SPOT/VEGETATION, Terra/MODIS satellite data
Elizabeth Ferreira   +3 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

CROP DATA RETRIEVAL USING EARTH OBSERVATION DATA TO SUPPORT AGRICULTURAL WATER MANAGEMENT [PDF]

open access: yesEngenharia Agrícola, 2019
Accurate crop data are essential for reliable irrigation water requirements (IWR) calculations, which can be acquired during the crop growth season for a given region using earth observation (EO) satellite time series. In addition, a relationship between
João Rolim   +4 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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