Results 51 to 60 of about 78,085 (310)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Coefficient Of Parentage For Crop Hybridization

open access: yes, 2007
{"references": ["Chen, Zhengxin and Zhu, Quiming, \"Query construction for user-guided\nknowledge discovery in databases\", Information Sciences 109 (1-4),\n1998, pp. 49-64.", "Fan, Jianhua and Li, Deyi (1998) \"Overview of data mining and\nknowledge discovery\", Journal of Computer Science and Technology.\n13 (4), 1998, pp 348-368.", "H.K Grewal ...
Manpreet Singh   +2 more
openaire   +2 more sources

Temporal Downscaling of Crop Coefficient and Crop Water Requirement from Growing Stage to Substage Scales

open access: yes, 2012
Crop water requirement is essential for agricultural water management, which is usually available for crop growing stages. However, crop water requirement values of monthly or weekly scales are more useful for water management.
Songhao Shang
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Effects of Saline Irrigation Water Applications on Evapotranspiration Partitioning and Crop Coefficient of Tomato Grown in Mediterranean-Type Greenhouses

open access: yesAgronomy
Accurate information regarding crop evapotranspiration (ETc) and its components is essential for proper water management. Salinity has become increasingly serious in many parts of the world, affecting the use of saline water in irrigation for various ...
Gulcin Ece Aslan   +5 more
doaj   +1 more source

Estimation of Crop Water Deficit in Lower Bari Doab, Pakistan Using Reflection-Based Crop Coefficient

open access: yesISPRS International Journal of Geo-Information, 2020
There is a global realization in all governmental setups of the need to provoke the efficient appraisal of crop water budgeting in order to manage water resources efficiently.
Muhammad Asif Javed   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Evapotranspiration and crop coefficient of cucumber in greenhouse [PDF]

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2003
The evapotranspiration (ETc) and crop coefficient (Kc) of cucumber in a greenhouse were determined during the winter-spring season in Piracicaba, SP, Brazil. Crop was irrigated with water of three different levels of salinity: S1 = 1.5, S2 = 3.1 and S3 = 5.2 dS m-1.
Blanco, Flávio F., Folegatti, Marcos V.
openaire   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Relationship between crop coefficient and soil evaporation in forage grassland under sprinkler irrigation in Lhasa Valley

open access: yesGuan'gai paishui xuebao
【Objective】 Crop coefficient and soil evaporation are two important parameters for calculating evapotranspiration in terrestrial ecosystems but they are dependent on many factors.
XU Bing   +4 more
doaj   +1 more source

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