Results 71 to 80 of about 2,236,452 (278)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Factors Affecting White-Tailed Deer-Browsing Rates on Early Growth Stages of Soybean Crops

open access: yesHuman-Wildlife Interactions, 2017
White-tailed deer (Odocoileus virginanus) damage to soybean crops is a concern for soybean producers. Although researchers have documented decreases in the intensity of deer-browse on soybean plants as the growing season progresses, an understanding of ...
Gregory M. Colligan   +3 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Hail Damage Disaster Recovery Web site Offers Crop Information

open access: yes, 2009
ISU Extension has set up a Hail Damage – Disaster Recovery Web site in response to the needs of Iowa producers making hail damage decisions. This site includes information on topics listed below, with additional information to be posted as harvest ...
Lang, Brian
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Testing for Moral Hazard and Ranking Farms by Their Inclination to Collect Crop Damage Compensations [PDF]

open access: yes
This paper tests for the extent of moral hazard problem within a Crop Damage Compensation (CDC) program that is similar to traditional multi peril crop insurances but is publicly funded and openly accessible for all farmers in Finland.
Myyra, Sami, Pietola, Kyosti
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

ADDITIVE VERSUS PROPORTIONAL PEST DAMAGE FUNCTIONS: WHY ECOLOGY MATTERS [PDF]

open access: yes
Economic analyses of pests typically assume damage is either additively separable from pest free yield or proportional to it. This paper describes the ecological assumptions required for additive and proportional damage functions to demonstrate that both
Mitchell, Paul D.
core  

The potential of crop management practices to reduce pollen beetle damage in oilseed rape [PDF]

open access: yes, 2017
A major problem associated with agricultural intensifcation over recent decades has been the development of insecticide resistance in crop pest populations.
Matthew P. Skellern   +3 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

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