Results 121 to 130 of about 3,389,301 (312)

Preventing Blood Clots in Hospitals: Improvement Collaborative Report National Recommendations and Improvement Toolkit

, 2018
This report shares learning from the collaborative, including which factors contributed to high levels of appropriate prophylaxis and to improvement. There was a higher level of appropriateness observed in orthopaedic and post-partum patients than in ...
National Medication Safety Improvement Programme
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Somaclonal variation as a tool for crop improvement

, 1995
Somaclonal variation is a tool that can be used by plant breeders. The review examines where this tool can be applied most effectively and the factors that limit or improve its chances of success.
Angela Karp, Karp, A.
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Reciprocal control of metabolic and chromatin regulators improves rice tolerance to heat

Nature Communications
Plant metabolic activities are regulated to adapt to the fluctuating environment for optimized growth, while interplay between metabolic and chromatin pathways plays an essential role in environmental adaptation.
Yaping Yue, Biao Liu, Qiutao Xu, Zhengting Chen, Jing Wang, Yu Zhao, Dao-Xiu Zhou   +6 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Impacts of CGIAR Crop Improvement and Natural Resource Management Research: A Review of Evidence [PDF]

This paper has examined the trends in funding and impacts of CGIAR research with a focus on distribution of economic benefits and sustainability of natural resources.
Pal, Suresh
core  

Quality Improvement Division Operational Plan 2016 [PDF]

, 2016
This is the second Operational Plan for the Quality Improvement Division (QID) since its establishment in 2015 and it builds on the work in 2015 to enable the HSE develop and implement a quality improvement agenda and capability across all levels of the ...
Quality Improvement Division
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Genome-wide association study for seedling heat tolerance under two temperature conditions in bread wheat (Triticum aestivum L.)

BMC Plant Biology
Background As the greenhouse effect intensifies, global temperatures are steadily increasing, posing a challenge to bread wheat (Triticum aestivum L.) production.
Chao Fu, Ying Zhou, Ankui Liu, Rui Chen, Li Yin, Cong Li, Hailiang Mao   +6 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source