Results 141 to 150 of about 3,389,301 (312)

Assessment of stability and yield performance of onion (Allium cepa L.) genotypes across diverse Indian environments

open access: yesScientific Reports
Onion productivity in India is strongly influenced by genotype × environment interaction (GEI), complicating the identification of stable and high-yielding cultivars.
Amar Jeet Gupta   +8 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Quality Improvement Division Operations Plan 2018

open access: yes, 2018
This is the Operational Plan for the Quality Improvement Division (QID) for 2018 and builds on the work done since 2015 to enable the HSE develop and implement a quality improvement agenda and capability across all levels of the ...
Quality Improvement Division
core  

Cross-validation to select the optimum rank for a reduced-rank approximation to multivariate data

open access: yes
In this paper we consider the Gabriel form of cross-validation (CV) and we investigate how to estimate the optimum rank for lower rank approximations of any dataset that can be written in matrix form, with particular application in multivariate analysis ...
Krzanowski W.J.   +3 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Crop genetic resource policy: the role of ex situ genebanks [PDF]

open access: yes
The world-wide capacity of genebanks for ex situ conservation of crop genetic resources has increased greatly since the 1970s, improving the access of crop breeders to landraces and wild and weedy relatives.
Wright, Brian D.
core  

Recent advancement and perspectives of molecular markers for resistance against purple blotch disease in onion (Allium cepa)

open access: yesDiscover Plants
Purple blotch, caused by Alternaria porri (Ellis) Cifferi, is one of the most destructive fungal foliar disease of onions globally. Development of cultivars exhibiting enhanced genetic resistance to biotic stressors is the most effective, economical, and
S. Santhiya   +6 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

National Quality Improvement Team Annual Report 2017

open access: yes, 2018
This report is a high level overview of work completed by the National Quality Improvement Team (formerly known as the Quality Improvement Division) in 2018.
National Quality Improvement Team
core  

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