Results 51 to 60 of about 925,219 (277)

Effect of organic, low-input and conventional production systems on yield and diseases in winter barley [PDF]

, 2007
The effect of organic, low-input and conventional management practices on barley yield and disease incidence was assessed in field trials over two years.
Cooper, J. M., Leifert, C., Lueck, L., Schmidt, C. S., Shotton, P. N., Turnbull, C.   +5 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Recombination and transposition drive genomic structural variation potentially impacting life history traits in a host-generalist fungal plant pathogen

BMC Biology
Background An understanding of plant pathogen evolution is important for sustainable management of crop diseases. Plant pathogen populations must maintain adequate heritable phenotypic variability to survive.
Mark C. Derbyshire, Toby E. Newman, Yuphin Khentry, Pippa J. Michael, Sarita Jane Bennett, Ashmita Rijal Lamichhane, Carolyn Graham-Taylor, Subhash Chander, Claudia Camplone, Simone Vicini, Laura Esquivel-Garcia, Cathy Coutu, Dwayne Hegedus, John Clarkson, Kurt Lindbeck, Lars G. Kamphuis   +15 more
doaj   +1 more source

Appendix I: References Cited [PDF]

, 2008
Annual summary of field crop insect management trials, Department of Crop Services, University of Illinois. Providing accurate and unbiased evaluations of insect control products and management strategies to assist growers in Illinois.University of ...
Integrated Pest Management
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Agri Watch: Precision Plant Health Monitoring using Deep Learning [PDF]

E3S Web of Conferences
The growth of deep learning technologies allows us to achieve higher accuracy in the classification of plant diseases, as well as in other domains. This research reveals the performance of several DL approaches, including custom convolutional neural ...
Krishna Ujjwal, Bharadwaj Sreepada, Kaswan Vinit, Kumar Anuraj, Kaur Gursimran, Rana Pooja   +5 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Growers’ perceptions and attitudes towards fungicide resistance extension services

Scientific Reports
Agricultural extension services have been successful in promoting knowledge sharing and innovation in agriculture. However, the adoption of new agricultural practices, particularly in integrated pest management, has been slow.
Toto Olita, Michelle Stankovic, Billy Sung, Megan Jones, Mark Gibberd   +4 more
doaj   +1 more source

Management of vegetable crop residues for reducing nitrate leaching losses in intensive vegetable rotations [PDF]

, 2012
Crop residues of field vegetables are often characterized by large amounts of biomass with a high N-content. Despite low soil temperatures during autumn, high rates of N mineralization and nitrification still occur causing important N-losses through ...
Agneessens, Laura, Crappé, Sara, De Neve, Stefaan, Elsen, Annemie, Goovaerts, Ellen, Van de Sande, Tomas, Vandecasteele, Bart   +6 more
core   +1 more source