Results 71 to 80 of about 422,484 (314)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Influence of compost supplemented with jatropha cake on soil fertility, growth, and yield of maize (zea mays L.) in a degraded soil of Ilorin, Nigeria

International Journal of Recycling of Organic Waste in Agriculture, 2018
Purpose This study was conducted to determine the effect of compost supplemented with jatropha cake on maize (Zea mays L) yield in a degraded soil and their residual effects on soil fertility in Ilorin, Nigeria.
Adebayo Abayomi Olowoake, Oluremi Solomon Osunlola, James Adebayo Ojo   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

National technical guideline on mechanized wet direct-seeding for increased productivity, quality, and reduced carbon footprint in rice production in the Mekong River Delta [PDF]

The national technical guideline on mechanized wet direct-seeding for increased productivity, quality, and reduced carbon footprint in rice production in the Mekong River Delta (MRD) was issued on 31 October 2023 by Department of Crop Production, MARD of
Department of Crop Production, Vietnam
core  

Vineyard “Naturalness”: Principles and Challenges

Australian Journal of Grape and Wine Research
The notion of “natural wines” has gained traction, yet the concept of vineyard naturalness remains largely neglected, often conflated with “organic” or “regenerative” viticulture.
Stefano Poni, Tommaso Frioni, Matteo Gatti   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

National technical guideline on rice straw management towards circular economy and low emission in the Mekong River Delta [PDF]

The national technical guideline on rice straw management towards circular economy and low emission in the Mekong River Delta (MRD) was issued on 10 July 2023 by Department of Crop Production, Ministry of Agriculture and Rural Development of Viet Nam ...
Department of Crop Production, Vietnam
core  

Phenotypic and molecular characterization of Hessian fly resistance in diploid wheat, Aegilops tauschii

BMC Plant Biology, 2019
Background The Hessian fly (Mayetiola destructor), belonging to the gall midge family (Cecidomyiidae), is a devastating pest of wheat (Triticum aestivum) causing significant yield losses.
Jill A. Nemacheck, Brandon J. Schemerhorn, Steven R. Scofield, Subhashree Subramanyam   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The influence of tillage on selected biological parameters

Plant, Soil and Environment, 2006
The influence of tillage (conventional and non-tillage) on selected soil microbial properties was studied. The experiment focused on tillage that was launched in Prague-Ruzyne in 1997. The experiment included the following variants: conventional tillage,
O. Mikanová, M. Javůrek, M. Vach, A. Markupová   +3 more
doaj   +1 more source