Results 91 to 100 of about 6,944,871 (310)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

WERE U.S. CROP YIELDS RANDOM IN RECENT YEARS? [PDF]

open access: yes
Crop Production/Industries,
Lin, Kuang-Hsing T., Seaver, Stanley K.
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Nano zinc oxide (ZnO) foliar nutrition improves yield, antioxidant defence, and zinc content in rice grown under Zn-deficient soil

open access: yesDiscover Nano
Conventional Zn fertilisers have poor use efficiency (
Gobinath Rajendran   +11 more
doaj   +1 more source

The Promotion of Alternative Crop Production Paradigms Should Be Founded on Proven Science-Based Approaches. [PDF]

open access: yesPlants (Basel)
Recent discourse on the need to adopt alternative approaches to sustainable crop production has strongly criticized modern, usually referred to as “industrial”, agriculture as the main cause of environmental problems and a loss of ...
Lenné J, Wood D.
europepmc   +2 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Land Use Consequences of Crop Insurance Subsidies [PDF]

open access: yes
There have long been concerns that federal crop insurance subsidies may significantly impact land use decisions. It is well known that classical insurance market information asymmetry problems can lead to a social excess of risky land entering crop ...
Hennessy, David A.   +2 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Evaluating Dryland Crop/Livestock System Alternatives for Risk Management under Declining Irrigation in the Texas Panhandle [PDF]

open access: yes
Production budgets for dryland crop and crop/livestock systems are developed to estimate yields, costs and returns for dryland wheat and sorghum and for alternative dryland crop/livestock systems. A crop simulation model aids yield estimation.
Lust, David G.   +3 more
core  

Effect of Soil Physical State on the Earthworms in Hungary

open access: yesApplied and Environmental Soil Science, 2010
Hungarian authors have long been discussing the role of earthworms in improving soil productivity. Earthworm counts in our higher quality soils are similar to those found in soils where more attention is paid to earthworm activity.
Marta Birkas   +4 more
doaj   +1 more source

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