Results 101 to 110 of about 6,944,871 (310)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Comparative assessment of perennial grasses for restoring degraded semi-arid agroecosystems under contrasting moisture regimes

Discover Soil
Although perennial grasses are increasingly recognized for restoring degraded lands, their restoration potential under contrasting moisture regimes in semi-arid agroecosystems remains poorly understood.
Mukesh Choudhary, Mahendra Prasad, Anoop Kumar Dixit, Sita Ram Kantwa, Sonu Kumar Mahawer, Dana Ram Palsaniya   +5 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Sustainable Energy Crop Production: A Case Study for Sugarcane and Cassava Production in Yunnan, China [PDF]

The possibility of using biomass as a source of energy in reducing the greenhouse-effect imposed by carbon dioxide emission and relieving energy crisis is a matter of great interest, such as bioethanol production.
Zhang, Sizhu, Zhang, Yu, Ni, Jianhong
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Crop Flexibility in Dryland Corn and Soybeans Using Predicted Yields and Prices [PDF]

Crop Production/Industries,
Yamoah, Charles F., Dias, Weeratilake, Helmers, Glenn A.   +2 more
core  

Onion (Allium cepa L.) and Drought: Current Situation and Perspectives

Scientifica
Onions (Allium cepa L.) are the second most commonly produced and consumed vegetable worldwide due to their economic, nutritional, and medicinal benefits.
Oladé Charles Sansan, Vincent Ezin, Mathieu Anatole Tele Ayenan, Ifagbémi Bienvenue Chabi, Hubert Adoukonou-Sagbadja, Aliou Saïdou, Adam Ahanchede   +6 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

U.S. Cotton Acreage Response Due to Subsidized Crop Insurance [PDF]

subsidy per pound, rate of return simultaneous, panel, fixed effects, Agricultural and Food Policy, Crop Production/Industries, Risk and Uncertainty,
Tronstad, Russell, Bool, Romilee
core  

Application of slow-controlled release fertilizer coordinates the carbon flow in carbon-nitrogen metabolism to effect rice quality

BMC Plant Biology
Slow-controlled release fertilizers are experiencing a popularity in rice cultivation due to their effectiveness in yield and quality with low environmental costs.
Zhengrong Jiang, Qiuli Chen, Dun Liu, Weike Tao, Shen Gao, Jiaqi Li, Chunhao Lin, Meichen Zhu, Yanfeng Ding, Weiwei Li, Ganghua Li, Soulaiman Sakr, Lihong Xue   +12 more
doaj   +1 more source