Results 101 to 110 of about 422,484 (314)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
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Discover NanoConventional Zn fertilisers have poor use efficiency (
Gobinath Rajendran +11 more
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Effect of Soil Physical State on the Earthworms in Hungary
Applied and Environmental Soil Science, 2010 Hungarian authors have long been discussing the role of earthworms in improving soil productivity. Earthworm counts in our higher quality soils are similar to those found in soils where more attention is paid to earthworm activity.
Marta Birkas +4 more
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Plant Protection Science, 2004 Seeds from atrazine resistant plants of black nightshade (Solanum nigrum L.) were collected at the railway station Prague-Vršovice, seeds from susceptible plants in Vyšehořovice (Prague East district). Tests on emergence showed that in both resistant and
Jaroslav Salava +2 more
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The Factorial Analysis of Crop Productivity
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1954 Summary The main purpose of this paper is to illustrate how the methods of factor analysis developed by psychologists to analyse what might be called mental productivity may be usefully applied to agricultural data, in order to deal with such problems as crop productivity.
openaire +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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A REVIEW AND EVALUATION OF WEATHER-CROP YIELD MODELS [PDF]
The purpose of this paper is the relatively limited one of reviewing the literature for models which develop specific relationships between climatic variables and crop yields.
Geigel, Joanne M., Sundquist, W. Burt
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
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Sustainable Energy Crop Production: A Case Study for Sugarcane and Cassava Production in Yunnan, China [PDF]
The possibility of using biomass as a source of energy in reducing the greenhouse-effect imposed by carbon dioxide emission and relieving energy crisis is a matter of great interest, such as bioethanol production.
Zhang, Sizhu, Zhang, Yu, Ni, Jianhong
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