Results 21 to 30 of about 589,680 (310)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effect of wheat production system components on food preference in rats [PDF]

, 2008
In the study presented the effects of two major system components - fertility management and crop protection - were tested in a rat preference test for the first time.
Cooper, Dr. Julia M., Leifert, Prof. Carlo, Lueck, Dr. Lorna, Shiel, Dr. Robert S., Velimirov, Dr. Alberta   +4 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

NlugOBP1 in Nilaparvata lugens involved in the perception of repellent agent geraniol

Scientific Reports
The brown planthopper Nilaparvata lugens (Stål) is one of the most prominent rice pests. Current methods for effectively controlling N. lugens primarily involve cultivating resistant varieties or synthesizing insecticides.
Ke Ke, Shuai Wu, Ke Hu, Xun Liao, Ming Li, Rongyu Li   +5 more
doaj   +1 more source

Effect of organic, low-input and conventional production systems on yield and diseases in winter barley [PDF]

, 2007
The effect of organic, low-input and conventional management practices on barley yield and disease incidence was assessed in field trials over two years.
Cooper, J. M., Leifert, C., Lueck, L., Schmidt, C. S., Shotton, P. N., Turnbull, C.   +5 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Agroecosystem sustainability index ASI for measuring environmental and socioeconomic sustainability

npj Sustainable Agriculture
Developing scalable, context-specific sustainability assessments is a major challenge in agroecosystem management. This study presents the Agroecosystem Sustainability Index (ASI), a novel tool integrating environmental, economic, and social indicators ...
Donia Jendoubi Mühlematter, Stephen J. Maund, Mafalda Nina   +2 more
doaj   +1 more source

Entomopathogenic fungi as a promising biological control agent against banana fruit scarring beetle, Basilepta subcostata (Jac.) (Chrysomelidae: Coleoptera)

Egyptian Journal of Biological Pest Control, 2021
Background Banana fruit scarring beetle (BFSB), Basilepta subcostata (Jac.) (Chrysomelidae:Coleoptera), is an important insect pest feeds on leaf and fingers, which affects the cosmetic value of the fruit.
Velavan Viswakethu, Padmanaban Balakrishanan, Loganathan Murugan, Baskar Narayana swamy, Uma Subbaraya   +4 more
doaj   +1 more source

Results of trials with poppy seed (Papaver somniferum) in organic and integrated production technology. [PDF]

, 2010
The influence of organic and integrated management practices on poppy yield, pests and disease incidence was assessed in field trials in 2009. Crop management based on mineral fertilisers application and chemosynthetic pesticides treatment significantly
Dvorak, Petr, Hajkova, Miroslava, Kazda, Jan, Kuchtova, Perla, Plachka, Eva   +4 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source