Results 51 to 60 of about 117,465 (316)

Efficacy of Hexanal Field Spray on the Postharvest Life and Quality of Papaya Fruit (Carica papaya L.) in Kenya

Advances in Agriculture, 2022
Papaya is a thin-skinned fruit that ripens and softens over a very short time, usually in 3 days, predisposing the fruit to physical damage and phyto-pathogen invasion even with careful handling further shortening postharvest shelf life. The objective of
Margaret J. Hutchinson, John R. Ouko, Peninah M. Yumbya, Jane L. Ambuko, Willis O. Owino, Jayasankar Subramanian   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Novel approach toward the understanding of genetic diversity based on the two types of amino acid repeats in Erwinia amylovora

Scientific Reports, 2023
Erwinia amylovora is a notorious plant pathogenic bacterium of global concern that has devastated the apple and pear production industry worldwide. Nevertheless, the approaches available currently to understand the genetic diversity of E.
Hyeonheui Ham, Dong Suk Park
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Development of accessible and scalable maize pollen storage technology

Communications Biology
The inherent short lifespan of Zea mays (maize, corn) pollen hinders crop improvement and challenges the hybrid seed production required to produce food, fuel, and feed.
Jared D. Carter, Jay A. Dinwiddie, Sarah E. Hill-Skinner, Nicholas D. Polge, Ankit I. Fajalia, George R. Hodges, John H. E. Hone, Stanley C. S. Lai, David B. Medeiros, Lothar O. E. Langer, Isabelle S. Besse, Cristobal M. Gonzalez, Trey A. Woodall, David S. Skibbe   +13 more
doaj   +1 more source

Oleaginous crops as integrated production platforms for food, feed, fuel and renewable industrial feedstock

Oilseeds and fats, crops and lipids, 2014
The world faces considerable challenges including how to produce more biomass for food, feed, fuel and industrial feedstock without significantly impacting on our environment or increasing our consumption of limited resources such as water or petroleum ...
Beaudoin Frédéric, Sayanova Olga, Haslam Richard P., Bancroft Ian, Napier Johnathan A.   +4 more
doaj   +1 more source

Studies on common root rot and Bipolaris sorokiniana in wheat and barley in South Australia [PDF]

, 1992
201p.Thesis (Ph.D.)--University of Adelaide, Depts.
Whittle, Peter James Latimer
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Reaction of transgenic plum cv. HoneySweet to the Plum pox virus after a severe infection of Monilinia sp. - short communication

Plant Protection Science, 2019
Resistance to Plum pox virus (PPV) in transgenic Prunus domestica L., clone C5 (cv. HoneySweet) was evaluated in a regulated field in the Czech Republic for fifteen years (2002-2016). PPV mild symptoms appeared in C5 trees only in several leaves situated
Jaroslav Polák, Tereza Neubauerová, Petr Komínek, Jiban Kumar Kundu   +3 more
doaj   +1 more source