Results 31 to 40 of about 29,595 (258)

Crop yield and water use efficiency in response to long-term diversified crop rotations

open access: yesFrontiers in Plant Science, 2022
Crop production and water productivity may be impacted by diverse crop rotation and management practices. A field study was conducted from 2017-2020 in the Loess Plateau to evaluate the effects of crop rotation sequences on pre-planting and post-harvest ...
Zhengjun Cui   +20 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Assimilation and return of nutrient elements by plants in soil and impact of crop residues on soil fertility in short cotton rotations

open access: yesРастениевъдни науки, 2015
To develop a highly efficient the short cycled rotations which provide conservation and improvement soil fertility, of Silt Loam Calcic Xerosol (FAO, 2003) of Tashkent region and the results of the investigations recommend and inculcate to agricultural ...
Abdulaly Iminov   +2 more
doaj  

Quantity and Nature of Water-Extractable Organic Matter from Sandy Loam Soils with Potato Cropping Management

open access: yesAgricultural & Environmental Letters, 2016
This work evaluated the level and nature of water-extractable soil organic matter (WEOM) from a 6-yr potato ( L.) crop rotation field experiment. The content of WEOM was higher in continuous potato soils than in the 2-yr and 3-yr crop rotation soils ...
Zhongqi He   +5 more
doaj   +1 more source

The Composition of the Organic Matter Fractions of Loamy Sand after Long-Term FYM Application without Liming

open access: yesAgronomy, 2022
The key to soil organic matter management is understanding the transformation processes of fresh organic matter to permanent humus that control soil organic carbon dynamics.
Dorota Pikuła, Olga Ciotucha
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Brain physiology during photoperiod-related caste determination in the primitively eusocial wasp Polistes jokahamae

open access: yesScientific Reports
Adult females of the primitively eusocial wasp Polistes jokahamae can change caste in response to photoperiod length. Short-day photoperiod females store more lipids but have less developed ovaries for hibernation (becoming gynes), whereas long-day ...
Ken Sasaki   +2 more
doaj   +1 more source

Unveiling the Effects of Crop Rotation on Cropland Soil pH Mapping: A Remote Sensing-Based Soil Sample Grouping Strategy

open access: yesRemote Sensing
Crop rotation affects soil pH by disturbing H+ production and consumption within soil–crop systems, primarily through fertilization, irrigation, cropping, and harvest. Studies have shown that crop rotation improves soil organic matter prediction. However,
Yuan Liu   +11 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

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