Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Optimization of crop rotation calendar to maximize system-level productivity under climate change
Crop rotation offers multifaceted benefits for climate change adaptation and mitigation. As rising temperatures shorten the crop duration from sowing to harvest, it is necessary to adjust the rotation order and sowing dates of crops in a rotation system.
Keach Murakami, Toshichika Iizumi
doaj +1 more source
Designing crop rotations in organic and low-input agriculture: Evaluation of pre-crop effects [PDF]
In this overview, the preceding effects of crop pairs are classified by establishing schematic diagrams for use in crop rotation planning in low external input or organic agricultural systems.
Kolbe, Hartmut
core
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Effect of crop rotation on soil nutrient balance and weediness in soddy podzolic organic farming fields [PDF]
The nutrient balance in different crop rotations under organic cropping system has been investigated in Latvia at the Institute of Agricultural Resources and Economics since 2006.
Zarina, Liga, Zarina, Livija
core
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Exploring the factors driving farmers’ crop rotation intention and behavior can provide a scientific foundation for enhancing crop rotation policies. Utilizing 448 micro-research samples from three counties in Heilongjiang Province, a structural equation
Rui Zhang +3 more
doaj +1 more source
Influence of Previous Crop on Durum Wheat Yield and Yield Stability in a Long-term Experiment
Long-term experiments are leading indicators of sustainability and serve as an early warning system to detect problems that may compromise future productivity. So the stability of yield is an important parameter to be considered when judging the value of
Matteo Stelluti +2 more
doaj +1 more source
Crop rotation modelling—A European model intercomparison
Diversification of crop rotations is considered an option to increase the resilience of European crop production under climate change. So far, however, many crop simulation studies have focused on predicting single crops in separate one-year simulations. Here, we compared the capability of fifteen crop growth simulation models to predict yields in crop
Kollas, Chris +40 more
openaire +7 more sources

