Results 181 to 190 of about 972,870 (316)

Scalable, Low‐Cost, Freeze‐Resistant Hydrogels by Alkali‐Polyphenol‐Triggered Polymerization for Low‐Temperature Self‐Powered Triboelectric Sensor

open access: yesAdvanced Science, EarlyView.
Leveraging the multidimensional self‐catalytic merits of the alkali‐polyphenol synergistic self‐catalytic platform, this work delineates the intrinsic mechanism governing the regulation of hydrogel properties and puts forward an innovative design paradigm for frost‐tolerant electrode materials, providing critical scientific insights and technical ...
Mengting Zhou   +10 more
wiley   +1 more source

Irrigation and inequalities in the Senegal River Delta. [PDF]

open access: yesPLoS One
Sylla EHM   +5 more
europepmc   +1 more source

A Novel CsYABBY3‐CsAS1 Feedback Loop Coordinates Trichome Differentiation and Cannabinoid Biosynthesis in Cannabis sativa L.

open access: yesAdvanced Science, EarlyView.
A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu   +18 more
wiley   +1 more source

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

open access: yesAdvanced Science, EarlyView.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao   +6 more
wiley   +1 more source

Functionally rich crop rotations increase calorie and macronutrient outputs across Europe. [PDF]

open access: yesNat Food
Vico G   +23 more
europepmc   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Development of herbicide-resistant peanut via prime editing and optimization of editing efficiency. [PDF]

open access: yesPlant Physiol
Xue L   +11 more
europepmc   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

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