Results 1 to 10 of about 191,618 (313)

Genetic and epigenetic mechanisms influencing acute to chronic postsurgical pain transitions in pediatrics: Preclinical to clinical evidence

Canadian Journal of Pain, 2021
Background Chronic postsurgical pain (CPSP) in children remains an important problem with no effective preventive or therapeutic strategies. Recently, genomic underpinnings explaining additional interindividual risk beyond psychological factors have been
Adam. J. Dourson, Adam. Willits, Namrata.G.R. Raut, Leena Kader, Erin Young, Michael.P. Jankowski, Vidya Chidambaran   +6 more
doaj   +1 more source

Resequencing of 558 Chinese mungbean landraces identifies genetic loci associated with key agronomic traits

Frontiers in Plant Science, 2022
Mungbean is a warm-season annual food legume and plays important role in supplying food and nutritional security in many tropical countries. However, the genetic basis of its agronomic traits remains poorly understood.
Xuesong Han, Li Li, Hongwei Chen, Liangjun Liu, Longqin Sun, Xingmin Wang, Yantao Xiang, Zhenghuang Wan, Changyan Liu   +8 more
doaj   +1 more source

High-Throughput Genome-Wide Genotyping To Optimize the Use of Natural Genetic Resources in the Grassland Species Perennial Ryegrass (Lolium perenne L.)

G3: Genes, Genomes, Genetics, 2020
The natural genetic diversity of agricultural species is an essential genetic resource for breeding programs aiming to improve their ecosystem and production services.
Thomas Keep, Jean-Paul Sampoux, José Luis Blanco-Pastor, Klaus J. Dehmer, Matthew J. Hegarty, Thomas Ledauphin, Isabelle Litrico, Hilde Muylle, Isabel Roldán-Ruiz, Anna M. Roschanski, Tom Ruttink, Fabien Surault, Evelin Willner, Philippe Barre   +13 more
doaj   +1 more source

Genome wide association study of growth and feed efficiency traits in rabbits

World Rabbit Science, 2023
Feed efficiency is a major production trait in animal genetic breeding schemes. To further investigate the genetic control of feed efficiency in rabbits, we performed a genome-wide association study (GWAS) for growth and feed efficiency on 679 rabbits ...
Hervé Garreau, Yann Labrune, Hervé Chapuis, Julien Ruesche, Juliette Riquet, Julie Demars, Florence Benitez, François Richard, Laurence Drouilhet, Olivier Zemb, Hélène Gilbert   +10 more
doaj   +1 more source

Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

Exploration of Medicine, 2021
Aim: Substance use disorders (SUD) result in substantial morbidity and mortality worldwide. Opioids, and to a lesser extent cocaine, contribute to a large percentage of this health burden.
Richard Sherva, Congcong Zhu, Leah Wetherill, Howard J. Edenberg, Emma Johnson, Louisa Degenhardt, Arpana Agrawal, Nicholas G. Martin, Elliot Nelson, Henry R. Kranzler, Joel Gelernter, Lindsay A. Farrer   +11 more
doaj   +1 more source

Using the power of innate immunoprofiling to understand vaccine design, infection, and immunity

Human Vaccines & Immunotherapeutics, 2023
In the field of immunology, a systems biology approach is crucial to understanding the immune response to infection and vaccination considering the complex interplay between genetic, epigenetic, and environmental factors.
Jennifer Connors, Gina Cusimano, Nathan Mege, Kyra Woloszczuk, Emily Konopka, Matthew Bell, David Joyner, Jennifer Marcy, Virginie Tardif, Michele A. Kutzler, Roshell Muir, Elias K. Haddad   +11 more
doaj   +1 more source

Genetic Basis Dissection for Eating and Cooking Qualities of Japonica Rice in Northeast China

Agronomy, 2020
The japonica rice in Northeast China is famous because of its high quality. Eating and cooking qualities (ECQs) are the most important factors that determine cooked rice quality.
Yaolong Yang, Xin Xu, Mengchen Zhang, Qun Xu, Yue Feng, Xiaoping Yuan, Hanyong Yu, Yiping Wang, Xinghua Wei   +8 more
doaj   +1 more source

Beyond the coding genome: non-coding mutations and cancer

Frontiers in Bioscience-Landmark, 2020
Latest advancements in genomics involving individuals from different races and geographical locations has led to the identification of thousands of common as well as rare genetic variants and copy number variations (CNVs). These studies have surprisingly
Kaivalya Walavalkar, Dimple Notani
doaj   +1 more source

A Multiple-Trait Bayesian Variable Selection Regression Method for Integrating Phenotypic Causal Networks in Genome-Wide Association Studies

G3: Genes, Genomes, Genetics, 2020
Bayesian regression methods that incorporate different mixture priors for marker effects are used in multi-trait genomic prediction. These methods can also be extended to genome-wide association studies (GWAS).
Zigui Wang, Deborah Chapman, Gota Morota, Hao Cheng   +3 more
doaj   +1 more source

Genome-Wide Association Analysis of Plant Height Using the Maize F1 Population

Plants, 2019
Drastic changes in plant height (PH) are observed when maize adapt to a higher plant density. Most importantly, PH is an important factor affecting maize yield.
Yong Zhang, Jiyu Wan, Lian He, Hai Lan, Lujiang Li   +4 more
doaj   +1 more source