Results 31 to 40 of about 174,316 (315)
G3: Genes, Genomes, Genetics, 2020 Exercise is recommended by health professionals across the globe as part of a healthy lifestyle to prevent and/or treat the consequences of obesity. While overall, the health benefits of exercise and an active lifestyle are well understood, very little ...
Louis P. Watanabe +3 more
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GWAS quality score for evaluating associated regions in GWAS analyses
Bioinformatics, 2023 Abstract Motivation The number of significantly associated regions reported in genome-wide association studies (GWAS) for polygenic traits typically increases with sample size. A traditional tool for quality control and identification of significant regions has been a visual inspection of how ...
Swapnil Awasthi +5 more
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Epigenetics, 2020 A major challenge in translating findings from genome-wide association studies (GWAS) to biological mechanisms is pinpointing functional variants because only a very small percentage of variants associated with a given trait actually impact the trait. We
Xiao Zhang +7 more
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Бюллетень сибирской медицины, 2020 We identified significant functions of susceptibility-genes and performed an analysis of pathway enrichment for Alzheimer’s disease, Parkinson’s disease and for both of them.
N. Yu. Chasovskikh +2 more
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Cluster analysis of milk fat yield trait in dairy cows using meta-analysis of the genome-wide association studies [PDF]
پژوهش های علوم دامی, 2022 Introduction: Cow's milk is one of the most important animal products for any country and known as an important source for fat and protein originated from animals (Fenelon and Guinee, 1999, Martini et al., 2016).
S Bakhshalizadeh1, S Zerehdaran2* and A Javadmanesh3
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Features of functional annotation of rheumatoid arthritis susceptibility genes by Cytoscape
Бюллетень сибирской медицины, 2020 Aim. To evaluate the functional annotation of genes associated with rheumatoid arthritis with different parameters of the ClueGO Cytoscape tool.Materials and methods.
N. Yu. Chasovskikh
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Thorax, 2011 We read with interest the recent article ‘Genome-wide association studies in lung disease’ by Artigas et al. 1 While we agree that a greater understanding of the biological pathways underlying disease development and progression (susceptibility) will be a major outcome from these genetic epidemiological studies, we suggest other benefits may also stem ...
Robert P, Young, Raewyn J, Hopkins
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Nature Genetics, 2009 Two genome-wide association studies for testicular cancer report associations at three new loci, including two candidate genes previously implicated in testicular development, KITLG (ligand for the receptor tyrosine kinase) and SPRY4 (sprouty 4).
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Maximum difference analysis: a new empirical method for genome-wide association studies
Italian Journal of Animal Science, 2016 The availability of high-density single nucleotide polymorphism (SNPs) panels for humans and, recently, for several livestock species has given a great impulse to genome-wide association studies towards the identification of genes associated with complex
Massimo Cellesi +6 more
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