Results 21 to 30 of about 174,316 (315)
Deep interpretability for GWAS
CoRR, 2020 Accepted at ICML 2020 workshop on ML Interpretability for Scientific ...
Deepak Sharma +6 more
openaire +2 more sources
BMC Genomics, 2014 Genome wide association studies (GWAS) have revealed a large number of links between genome variation and complex disease. Among other benefits, it is expected that these insights will lead to new therapeutic strategies, particularly the identification of new drug targets.
Cao, Chen, Moult, John
openaire +3 more sources
Achieving GWAS with homomorphic encryption [PDF]
BMC Medical Genomics, 2020 Abstract Background One way of investigating how genes affect human traits would be with a genome-wide association study (GWAS). Genetic markers, known as single-nucleotide polymorphism (SNP), are used in GWAS. This raises privacy and security concerns as these genetic markers can be used to identify individuals uniquely.
Jun Jie Sim +4 more
openaire +5 more sources
hchenBioinfo/Pancancer-GWAS-APA-analysis: CancerAPA v1.1
, 2023 We released the pipeline to analyze systematically cancer GWAS by integrating with 3'aQTLs across 49 tissues from GTEx ...
Chen wenyan, hchenBioinfo, Xudong Zou
core +1 more source
G3: Genes, Genomes, Genetics, 2019 One of the main pathogens affecting rainbow trout (Oncorhynchus mykiss) farming is the facultative intracellular bacteria Piscirickettsia salmonis. Current treatments, such as antibiotics and vaccines, have not had the expected effectiveness in field ...
Agustin Barria +6 more
doaj +1 more source
On the anniversary of Academician of the Russian Academy of Sciences Olga Silvestrovna Afanasenko
Биотехнология и селекция растений, 2023 In December 2023, the leading mycologist-phytopathologist of the Russian Federation, head of the laboratory of plant immunity to diseases of the All-Russian Research Institute of Plant Protection (VIZR), Doctor of Biological Sciences, Professor ...
I. G. Loskutov, O. N. Kovaleva
doaj +1 more source
I-GWAS: Privacy-Preserving Interdependent Genome-Wide Association Studies
, 2022 Genome-wide Association Studies (GWASes) identify genomic variations that are statistically associated with a trait, such as a disease, in a group of individuals.
Decouchant, Jérémie (author) +3 more
core +1 more source
Reducing GWAS Complexity [PDF]
Cell Cycle, 2016 Genome-wide association studies (GWAS) have revealed numerous genomic 'hits' associated with complex phenotypes. In most cases these hits, along with surrogate genetic variation as measure by numerous single nucleotide polymorphisms (SNPs) that are in linkage disequilibrium, are not in coding genes making assignment of functionality or causality ...
Dennis J, Hazelett +8 more
openaire +2 more sources
Genome-wide association study (GWAS) of high productivity classes in the Karachaevsky sheep breed [PDF]
Journal of Central European Agriculture, 2021 Using the Illumina Ovine Infinium HD BeadChip 600K DNA array, we performed a genome-wide association study (GWAS) in Karachaevsky breed sheep with different class evaluations (elite and super-elite).
Alexander Krivoruchko +3 more
doaj +1 more source
The Genetics of Primary Biliary Cholangitis: A GWAS and Post-GWAS Update
Genes, 2023 Primary biliary cholangitis (PBC) is a chronic, progressive cholestatic liver disease in which the small intrahepatic bile ducts are destroyed by autoimmune reactions. Among autoimmune diseases, which are polygenic complex traits caused by the combined contribution of genetic and environmental factors, PBC exhibits the strongest involvement of genetic ...
Hitomi, Yuki, Nakamura, Minoru
openaire +2 more sources