Results 21 to 30 of about 191,618 (313)

On beyond GWAS [PDF]

open access: yesNature Genetics, 2010
Analyses of genome-wide association studies (GWAS) show that common SNPs can account for the majority of the heritability of complex traits, but that there are likely to be limits to the usefulness of the current strategy of accumulating common variants of small effect for risk prediction.
openaire   +2 more sources

Achieving GWAS with homomorphic encryption [PDF]

open access: yesBMC Medical Genomics, 2020
Abstract Background One way of investigating how genes affect human traits would be with a genome-wide association study (GWAS). Genetic markers, known as single-nucleotide polymorphism (SNP), are used in GWAS. This raises privacy and security concerns as these genetic markers can be used to identify individuals uniquely.
Jun Jie Sim   +4 more
openaire   +6 more sources

On the anniversary of Academician of the Russian Academy of Sciences Olga Silvestrovna Afanasenko

open access: yesБиотехнология и селекция растений, 2023
In December 2023, the leading mycologist-phytopathologist of the Russian Federation, head of the laboratory of plant immunity to diseases of the All-Russian Research Institute of Plant Protection (VIZR), Doctor of Biological Sciences, Professor ...
I. G. Loskutov, O. N. Kovaleva
doaj   +1 more source

hchenBioinfo/Pancancer-GWAS-APA-analysis: CancerAPA v1.1

open access: yes, 2023
We released the pipeline to analyze systematically cancer GWAS by integrating with 3'aQTLs across 49 tissues from GTEx ...
Chen wenyan, hchenBioinfo, Xudong Zou
core   +1 more source

Single-Step Genome-Wide Association Study for Resistance to Piscirickettsia salmonis in Rainbow Trout (Oncorhynchus mykiss)

open access: yesG3: Genes, Genomes, Genetics, 2019
One of the main pathogens affecting rainbow trout (Oncorhynchus mykiss) farming is the facultative intracellular bacteria Piscirickettsia salmonis. Current treatments, such as antibiotics and vaccines, have not had the expected effectiveness in field ...
Agustin Barria   +6 more
doaj   +1 more source

Deep interpretability for GWAS

open access: yesCoRR, 2020
Accepted at ICML 2020 workshop on ML Interpretability for Scientific ...
Deepak Sharma   +6 more
openaire   +3 more sources

I-GWAS: Privacy-Preserving Interdependent Genome-Wide Association Studies

open access: yes, 2022
Genome-wide Association Studies (GWASes) identify genomic variations that are statistically associated with a trait, such as a disease, in a group of individuals.
Decouchant, Jérémie (author)   +3 more
core   +1 more source

Genome-wide association study (GWAS) of high productivity classes in the Karachaevsky sheep breed [PDF]

open access: yesJournal of Central European Agriculture, 2021
Using the Illumina Ovine Infinium HD BeadChip 600K DNA array, we performed a genome-wide association study (GWAS) in Karachaevsky breed sheep with different class evaluations (elite and super-elite).
Alexander Krivoruchko   +3 more
doaj   +1 more source

Reducing GWAS Complexity [PDF]

open access: yesCell Cycle, 2016
Genome-wide association studies (GWAS) have revealed numerous genomic 'hits' associated with complex phenotypes. In most cases these hits, along with surrogate genetic variation as measure by numerous single nucleotide polymorphisms (SNPs) that are in linkage disequilibrium, are not in coding genes making assignment of functionality or causality ...
Dennis J, Hazelett   +8 more
openaire   +2 more sources

Genetic Networks Underlying Natural Variation in Basal and Induced Activity Levels in Drosophila melanogaster

open access: yesG3: Genes, Genomes, Genetics, 2020
Exercise is recommended by health professionals across the globe as part of a healthy lifestyle to prevent and/or treat the consequences of obesity. While overall, the health benefits of exercise and an active lifestyle are well understood, very little ...
Louis P. Watanabe   +3 more
doaj   +1 more source

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