Results 21 to 30 of about 241,345 (301)

On the anniversary of Academician of the Russian Academy of Sciences Olga Silvestrovna Afanasenko

Биотехнология и селекция растений, 2023
In December 2023, the leading mycologist-phytopathologist of the Russian Federation, head of the laboratory of plant immunity to diseases of the All-Russian Research Institute of Plant Protection (VIZR), Doctor of Biological Sciences, Professor ...
I. G. Loskutov, O. N. Kovaleva
doaj   +1 more source

Genome-wide association study (GWAS) of high productivity classes in the Karachaevsky sheep breed [PDF]

Journal of Central European Agriculture, 2021
Using the Illumina Ovine Infinium HD BeadChip 600K DNA array, we performed a genome-wide association study (GWAS) in Karachaevsky breed sheep with different class evaluations (elite and super-elite).
Alexander Krivoruchko, Olesya Yatsyk, Anastasiya Kanibolockaya, Valery Kulintsev   +3 more
doaj   +1 more source

Genetic Networks Underlying Natural Variation in Basal and Induced Activity Levels in Drosophila melanogaster

G3: Genes, Genomes, Genetics, 2020
Exercise is recommended by health professionals across the globe as part of a healthy lifestyle to prevent and/or treat the consequences of obesity. While overall, the health benefits of exercise and an active lifestyle are well understood, very little ...
Louis P. Watanabe, Cameron Gordon, Mina Y. Momeni, Nicole C. Riddle   +3 more
doaj   +1 more source

Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis [PDF]

, 2013
Anti-tumor necrosis factor alpha (anti-TNF) biologic therapy is a widely used treatment for rheumatoid arthritis (RA). It is unknown why some RA patients fail to respond adequately to anti-TNF therapy, which limits the development of clinical biomarkers ...
A Parker, AI Catrina, AL Price, Alison Motsinger-Reif, AM van Gestel, Ann W. Morgan, Anne Barton, Anthony G. Wilson, Atsuo Taniguchi, B Devlin, Barbara E. Stranger, BE Stranger, BJ Scallon, C Liu, C Miceli-Richard, Chikashi Terao, Corinne Miceli, Cornelia F. Allaart, D Aeberli, D Plant, D Plant, DL Scott, Dorothee Diogo, EA Stahl, EA Stahl, EJ Toonen, Eli A. Stahl, Elizabeth W. Karlson, FM Batliwalla, Fumihiko Matsuda, Gert Jan Wolbink, GM Cooper, Gosia Trynka, H Canhao, Helena Canhao, Henk-Jan Guchelaar, Hisashi Yamanaka, IB McInnes, Irene E. van der Horst-Bruinsma, J Agnholt, J Cui, J Ernst, J Marchini, J. Bart A. Crusius, Jing Cui, Johan Askling, John D. Isaacs, João Eurico Fonseca, Katsunori Ikari, Kimme L. Hyrich, Koichiro Ohmura, L Klareskog, L Padyukov, Larry W. Moreland, LD Ward, Leonid Padyukov, Lindsey A. Criswell, M Martin, Manik Kuchroo, Marieke E. Doorenspleet, Marieke Herenius, Marieke J. H. Coenen, Mart van de Laar, Maša Umiċeviċ Mirkov, Michael E. Weinblatt, MJ Coenen, ML Prevoo, MM Soliman, Namrata Gupta, Nancy A. Shadick, Niek de Vries, O Stegle, Paul-Peter Tak, Peter K. Gregersen, Philip L. De Jager, PI de Bakker, Piet L. C. M. van Riel, PL De Jager, R Prajapati, Rene E. M. Toes, RM Plenge, Robert M. Plenge, Robert P. Kimberly, S Gudbrandsdottir, S Purcell, S. Louis Bridges, SA Gauthier, Saedis Saevarsdottir, Sara Wedrén, SG Tangye, Shigeki Momohara, Soumya Raychaudhuri, Tom W. J. Huizinga, Towfique Raj, Tsuneyo Mimori, Xavier Mariette, Y Okada, Yukinori Okada   +97 more
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GVHD meets GWAS [PDF]

Blood, 2015
In this issue of Blood , [Sato-Otsubo et al][1] perform a genome-wide association study (GWAS) to identify minor histocompatibility antigens associated with clinically relevant graft-versus-host disease (GVHD).[1][2] ![Figure][3] Schematic representation of different factors influencing ...
openaire   +2 more sources

Osteoporosis- and obesity-risk interrelationships: an epigenetic analysis of GWAS-derived SNPs at the developmental gene TBX15

Epigenetics, 2020
A major challenge in translating findings from genome-wide association studies (GWAS) to biological mechanisms is pinpointing functional variants because only a very small percentage of variants associated with a given trait actually impact the trait. We
Xiao Zhang, Kenneth C. Ehrlich, Fangtang Yu, Xiaojun Hu, Xiang-He Meng, Hong-Wen Deng, Hui Shen, Melanie Ehrlich   +7 more
doaj   +1 more source

Functional analysis and signaling pathway enrichment analysis of genes associated with Alzheimer’s disease and Parkinson’s disease

Бюллетень сибирской медицины, 2020
We identified significant functions of susceptibility-genes and performed an analysis of pathway enrichment for Alzheimer’s disease, Parkinson’s disease and for both of them.
N. Yu. Chasovskikh, A. Yu. Grechishnikova, D. V. Smirnov   +2 more
doaj   +1 more source

Cluster analysis of milk fat yield trait in dairy cows using meta-analysis of the genome-wide association studies [PDF]

پژوهش های علوم دامی, 2022
Introduction: Cow's milk is one of the most important animal products for any country and known as an important source for fat and protein originated from animals (Fenelon and Guinee, 1999, Martini et al., 2016).
S Bakhshalizadeh1, S Zerehdaran2* and A Javadmanesh3
doaj   +1 more source

On beyond GWAS [PDF]

Nature Genetics, 2010
Analyses of genome-wide association studies (GWAS) show that common SNPs can account for the majority of the heritability of complex traits, but that there are likely to be limits to the usefulness of the current strategy of accumulating common variants of small effect for risk prediction.
openaire   +2 more sources

GWAS quality score for evaluating associated regions in GWAS analyses

Bioinformatics, 2023
Abstract Motivation The number of significantly associated regions reported in genome-wide association studies (GWAS) for polygenic traits typically increases with sample size. A traditional tool for quality control and identification of significant regions has been a visual inspection of how ...
Swapnil Awasthi, Chia-Yen Chen, Max Lam, Hailiang Huang, Stephan Ripke, C Anthony Altar   +5 more
openaire   +2 more sources