Results 11 to 20 of about 133,124 (219)
Linkage disequilibrium and haplotype block structure in Portuguese Holstein cattle
Czech Journal of Animal Science, 2018 The objectives of this study were to estimate linkage disequilibrium (LD), describe and scan a haplotype block for the presence of genes that may affect milk production traits in Portuguese Holstein cattle.
Mohamed Mahmoud Ibrahim Salem +4 more
doaj +1 more source
Italian Journal of Animal Science, 2023 Single-nucleotide polymorphisms (SNPs) that are located near CpG sites have the potential to influence DNA methylation levels, leading to distinct patterns of DNA methylation.
Qi Shen +11 more
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Вавиловский журнал генетики и селекции, 2022 The yield and grain quality of spring and winter wheat significantly depends on varieties’ resistance to lodging, the genetic basis of this trait being quantitative and controlled by a large number of loci.
I. N. Leonova, E. V. Ageeva
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Entropy, 2020 Genome-wide association study (GWAS) has turned out to be an essential technology for exploring the genetic mechanism of complex traits. To reduce the complexity of computation, it is well accepted to remove unrelated single nucleotide polymorphisms ...
Hongping Guo +5 more
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Crick’s sequence hypothesis - a review
Communicative & Integrative Biology, 2019 Health care based on gene sequencing and genomics is increasingly becoming a reality: it is timely to review Crick’s sequence hypothesis for its fitness for this purpose.
Keith Baverstock
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Updates on Genes and Genetic Mechanisms Implicated in Primary Angle-Closure Glaucoma
The Application of Clinical Genetics, 2021 Altaf A Kondkar1– 3 1Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 2Glaucoma Research Chair in Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 3King Saud University ...
Kondkar AA
doaj
Enhancer Dysfunction in 3D Genome and Disease
Cells, 2019 Spatiotemporal patterns of gene expression depend on enhancer elements and other factors during individual development and disease progression. The rapid progress of high-throughput techniques has led to well-defined enhancer chromatin properties ...
Ji-Han Xia, Gong-Hong Wei
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Frontiers in Bioscience-ScholarBackground: Uterine fibroids (UF) is the most common benign tumour of the female reproductive system. We investigated the joint contribution of genome-wide association studies (GWAS)-significant loci and environment-associated risk ...
Liubov Ponomareva +2 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source