Results 51 to 60 of about 174,316 (315)

A decade in psychiatric GWAS research [PDF]

open access: yesMolecular Psychiatry, 2018
After more than 10 years of accumulated efforts, genome-wide association studies (GWAS) have led to many findings, most of which have been deposited into the GWAS Catalog. Between GWAS's inception and March 2017, the GWAS Catalog has collected 2429 studies, 1818 phenotypes, and 28,462 associated SNPs.
Tanya Horwitz   +4 more
openaire   +2 more sources

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung   +19 more
wiley   +1 more source

Smoking may be a risk factor for carpal tunnel syndrome: Insights from Mendelian randomization analysis

open access: yesTobacco Induced Diseases
Introduction It is currently uncertain whether smoking is a risk factor for carpal tunnel syndrome (CTS). This study aims to elucidate association between smoking and CTS using Mendelian randomization (MR) analysis.
Wei Shi+   +3 more
doaj   +1 more source

Identification of Novel Genetic Variants Associated with Insomnia and Migraine Comorbidity

open access: yesNature and Science of Sleep, 2022
Yu-Chin An,1 Chia-Lin Tsai,2 Chih-Sung Liang,3 Yu-Kai Lin,2 Guan-Yu Lin,2 Chia-Kuang Tsai,2 Yi Liu,2 Sy-Jou Chen,1 Shih-Hung Tsai,1 Kuo-Sheng Hung,4 Fu-Chi Yang2 1Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical ...
An YC   +10 more
doaj  

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

open access: yesAdvanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao   +14 more
wiley   +1 more source

A Nested Association Mapping Panel in Arabidopsis thaliana for Mapping and Characterizing Genetic Architecture

open access: yesG3: Genes, Genomes, Genetics, 2020
Linkage and association mapping populations are crucial public resources that facilitate the characterization of trait genetic architecture in natural and agricultural systems.
Marcus T. Brock   +3 more
doaj   +1 more source

The contribution of non-coding regulatory elements to cardiovascular disease [PDF]

open access: yesOpen Biology, 2020
Cardiovascular disease collectively accounts for a quarter of deaths worldwide. Genome-wide association studies across a range of cardiovascular traits and pathologies have highlighted the prevalence of common non-coding genetic variants within candidate
Diego Villar   +3 more
doaj   +1 more source

lanec-unifesspa/gwas-pd: Datapackage: Exploratory analysis of GWAS metanalyses of panic disorder

open access: yes, 2017
Data packages for the research project "Exploratory analyses of GWAS data on ...
Laboratório de Neurociências e Comportamento "Frederico Guilherme Graeff"
core   +1 more source

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease [PDF]

open access: yes, 2015
Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association study (GWAS) analysis of common SNPs.
Seedorf, Udo   +928 more
core   +1 more source

HDL GWAS

open access: yes, 2023
Created on 24 Aug 2023 - 09:49 by Fergus HamiltonThis data includes the GWAS of HDL particle counts performed in UK Biobank on the full Nightingame NMR sample. Full details are in the paper.
Fergus Hamilton (16875693)
core   +1 more source

Home - About - Disclaimer - Privacy