Results 71 to 80 of about 174,316 (315)
Advanced Science, EarlyView.TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang +18 more
wiley +1 more source
SMR added - GWAS and GTEx QTL integration
, 2019 The eQTL SMR results had been left out of the following repository due to an error https://zenodo.org/record/3518299 sQTL SMR results have also been uploaded to https://zenodo.org/record/3525070 ---------- sqlite version of these results are also ...
Abhiram Rao, GTEx GWAS subgroup
core +1 more source
Achieving High‐Density and Stress‐Resilient Maize Breeding Via Germplasm Innovation
Advanced Science, EarlyView.Global population growth and climate change have exacerbated the global food crisis. This perspective presents a conceptual framework focusing on enhancing population advantages. Several novel breeding objectives are proposed to improve density tolerance and stress resistance for yield improvement.
Xinlong Li +9 more
wiley +1 more source
Advanced Science, EarlyView.Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo +10 more
wiley +1 more source
Fine-mapping cis-regulatory variants in diverse human populations
eLife, 2019 Genome-wide association studies (GWAS) are a powerful approach for connecting genotype to phenotype. Most GWAS hits are located in cis-regulatory regions, but the underlying causal variants and their molecular mechanisms remain unknown.
Ashley Tehranchi +6 more
doaj +1 more source
mfrtn88/GWAS-analysis: Multi trait GWAS analysis
<p>R script for running multi-trait GWAS using summary stat results</p ...
Genomic_Analysis
core +1 more source
Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling
, 2011 Genome-wide association studies (GWAS) have identified SNPs associated with breast cancer. However, they offer limited insights about the biological mechanisms by which SNPs confer risk.
Chindo Hicks +2 more
core +1 more source
Advanced Science, EarlyView.In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu +13 more
wiley +1 more source
, 2023 (A) GWAS p-value histogram and (B) Manhattan plots for the four GWAS. Genome-wide significance level (−log10(5 × 10−8)) is indicated by the red line.
Dongjun Chung (213776) +4 more
core +1 more source
From Defense Executor to Engineering Target: Harnessing Lignin for Crop Resistance
Advanced Science, EarlyView.Lignin serves as both a physical and chemical executor of broad‐spectrum plant immunity. This review systematically summarizes classical and recent advances in lignin‐mediated immunity, outlines the multifaceted regulatory modules controlling lignification under biotic stress, discusses key physiological and biochemical mechanisms behind lignin‐based ...
Yanwen Yu +6 more
wiley +1 more source