Results 111 to 120 of about 5,013,800 (326)

The Tisza EGTC as a resilience tool for cross-border cooperation [PDF]

open access: yesAnnales Scientia Politica
This study examines how the Tisza European Grouping of Territorial Cooperation (Tisza EGTC) at the EU-Ukraine border has evolved from a legal-technical cooperation instrument into a resilience node in a multi-crisis context.
Melinda Istenes-Benczi
doaj  

Spatial integration in European cross-border metropolitan regions: A comparative approach [PDF]

open access: yes
This article analyses the process of spatial integration in ten European cross-border metropolitan regions. On the basis of three indicators, relating to flows of cross-border commuters, gross domestic product and the housing market, it suggests that ...
DECOVILLE Antoine   +3 more
core   +1 more source

ESHRE task force on ethics and law 15: Cross-border reproductive care [PDF]

open access: yes, 2008
This paper analyses the ethical aspects of cross-border reproductive care. Ethical questions are raised by some of the main reasons of cross-border travelling, i.e. law evasion and unequal access to treatment.
Cohen, J.   +5 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The Evolution of Inflation in Romania and the Republic of Moldova from 2015 to 2020

open access: yesACROSS
Inflation is a macroeconomic imbalance, a negative effect of the problems encountered by a national economy. The inflation process manifests differently from one state to another, and the occurrence of a new, unpredictable factor, as is the COVID-19 ...
Cristina FAZLI   +1 more
doaj  

Review on mechanisms and therapeutic advances in inorganic arsenic-induced reproductive system disorders

open access: yesAll Life
Inorganic arsenic (iAs), a toxic metalloid and recognized carcinogen, is widely distributed in the natural environment. Human exposure to iAs occurs via multiple pathways, leading to its accumulation and adverse effects on the human body.
Chengke Lu   +7 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Complex monitoring of the sports training level depending on dietary lipids

open access: yesACROSS
The essential components of food are proteins, fats and fuels. In this paper, we will analyze one of the main macronutrients: fats, also called lipids. First, dietary lipids are indeed exceptional sources of energy.
Veaceslav MANOLACHI
doaj   +1 more source

Cross-border merger and domestic welfare [PDF]

open access: yes
We consider the welfare effect of cross-border merger in presence of international R&D competition. Cross-border merger increases domestic welfare if the bargaining power of the foreign firm and the slope of the marginal cost of R&D are sufficiently low.
Arijit Mukherjee
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

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