Results 71 to 80 of about 162,634 (303)

The role of open borders and cross-border cooperation in regional growth across Europe

Regional Studies, Regional Science, 2020
This paper estimates the impacts of opening of borders and intensity of cross-border cooperation (CBC) on regional growth across European border regions. The difference-in-difference estimations show that the opening of national borders for free movement
Kadir Basboga
semanticscholar   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Romanian-Hungarian Cross Border Cooperation and the Impact on Transnational Institution Building and EU Fund Absorption

Analele Universităţii din Oradea. Relaţii Internaţionale şi Studii Europene, 2022
The border region is the collision point of cultures, religions, languages, administrations, legislations and economic influences. All these factors have substantial contribution to the development of the phenomenon called cross-border cooperation ...
POLGÁR István
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Regional economic development policy of cross-border cooperation: improving trends

Aspekti Publìčnogo Upravlìnnâ, 2014
Development of regional cross-border economic cooperation on the national and regional levels become increasingly important for the european integration of Ukraine. When forming the state regional policy, in the field of cross-border economic cooperation
V. F. Lutchak
doaj  

Local development and social responsibility to boost integration at the Romanian-Hungarian border

Analele Universităţii din Oradea. Relaţii Internaţionale şi Studii Europene
The border region is the collision point of cultures, religions, languages, administrations, legislations and economic influences. All these factors have substantial contribution to the development of the phenomenon called cross-border cooperation.
POLGÁR István
doaj   +1 more source

Turkish Border Regions and Cross-Border Cooperation in the EU Accession Process: The Case of Edirne and Kırklareli [PDF]

Megaron, 2014
Turkey has been engaging in cross-border cooperation projects for over a decade, and these accelerated following the granting of EU candidacy status to Turkey.
Ervin SEZGİN, Gülden ERKUT
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Evolution of the Concept of Cross-Border Cooperation in Russian and Foreign Historiography

RUDN Journal of World History
Despite cross-border cooperation being an object of study in the socio-humanitarian sciences, few studies comprehensively and purposefully overview its genesis, development, and transformation in historiography.
Anastasiia S. Tarasova
doaj   +1 more source