Results 141 to 150 of about 4,913,448 (308)
Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad +22 more
wiley +1 more source
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
A bomb from Australia [picture] /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross Feb 18th 1917"--In ink, lower left. "A Bomb From Australia"--In ink, upper margin; "Stan Cross 94 Aberdeen St Perth"--In pencil, on verso.; Also available in an
Cross, Stan, 1888-1977.
core
Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli +13 more
wiley +1 more source
Wally and the Major, tenth edition [picture] /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Wally and the Major, Tenth edition, By Stan Cross, 1/-"--In ink. "Stan Cross"--In pencil, lower right; "page 6"--In pencil, on note attached to verso.; Also available in ...
Cross, Stan, 1888-1977.
core
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai +13 more
wiley +1 more source
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross"--in ink, lower right. "Stan Cross"--in ink, lower right.
Cross, Stan, 1888-1977.
core
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross"--In ink, lower right. "In confidence"--In pencil, lower margin; "Stan Cross F. U.
Cross, Stan, 1888-1977.
core

