Results 91 to 100 of about 7,599,011 (305)

Wally and the Major [picture] : cross purposes /

open access: yes, 1968
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 8/195"--In ink, lower right. "8757 Fri Aug 16 Cross Purposes"--In ink, right margin; "8757"--In pencil, upper right corner; "6"--In pencil, upper left corner ...
Cross, Stan, 1888-1977.
core  

The Functional Value of Proper Nouns in Medical Texts

open access: yesArmenian Folia Anglistika, 2014
Medical terminology is the professional language of those who are directly or indirectly engaged in the art of healing. Medical texts contain a lot of Greek and Latin borrowings, metaphoric usages of some terms and also term-eponyms.
Marianna Ohanyan
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Wally and the Major [picture] : cross purposes /

open access: yes, 1969
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 9/66"--In ink, lower right. "8939 Tue Mar 18 Cross Purposes"--In ink, right margin; "8939"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
core  

Cross-Cultural Research: Methodological Challenges in Translating Meanings and Cultural Codes

open access: yesДискурс профессиональной коммуникации
Researchers in anthropology and psychology conducting cross-cultural comparative studies face a range of complex methodological challenges which significantly impact the validity and reliability of their findings. Paramount among these are issues related
V. N. Burkova   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Moral and Spiritual Causes of Mental Health Problems: Exploring the Spectrum of Perspectives of Indonesian Religious Leaders

open access: yesReligions
This article extends models that connect religion and spirituality (R/S) to the diagnosis and treatment of mental health problems to the Indonesian context, which is highly religious while being dominated by secular psychological approaches.
Mohammad Iqbal Ahnaf   +4 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Familia, comunidad y globalización: emprendedores indígenas wayuu como n-Culturals

open access: yes, 2020
23 páginasPurpose To explore the cultural context of Indigenous family entrepreneurs and to apply to them the concept of n-Culturals, thus contributing to validating the concept.
Felzensztein, Christian   +4 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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