Results 71 to 80 of about 358,595 (265)
On the Verbal Expression of Emotions: Language and Emotion Interplays
Armenian Folia Anglistika, 2014 In pre-historic times people used to communicate with each other through grunts, barks and roars. They gradually developed an elaborate set of sounds to express their emotions and convey their messages.
Ani Stepanyan
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Functional Value of Proper Nouns in Medical Texts
Armenian Folia Anglistika, 2014 Medical terminology is the professional language of those who are directly or indirectly engaged in the art of healing. Medical texts contain a lot of Greek and Latin borrowings, metaphoric usages of some terms and also term-eponyms.
Marianna Ohanyan
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Cross-Cultural Research: Methodological Challenges in Translating Meanings and Cultural Codes
Дискурс профессиональной коммуникацииResearchers in anthropology and psychology conducting cross-cultural comparative studies face a range of complex methodological challenges which significantly impact the validity and reliability of their findings. Paramount among these are issues related
V. N. Burkova +2 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
JPP (Jurnal Politik Profetik), 2017 This paper is aimed to find the cause of conflict in civil society by exploring the concept of intra-ethnic and inter-ethnic society offered by Ashutosh Varshney.
Batari Oja Andini
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Authenticity and Teacher’s Role in Project Based Learning
Armenian Folia Anglistika, 2016 Project based learning (PBL) is a student-centered teaching method that involves a dynamic classroom approach in which students gain knowledge and skills to explore and respond to an authentic and engaging problem or challenge.
Lusine Madoyan
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