Results 51 to 60 of about 7,599,011 (305)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
LGBT and Religious Negotiations: A Case Study of Youth Interfaith Forum on Sexuality (Yifos)
Most religious perspectives, particularly the conservative interpretation, emphasize the incompatibility of being a Lesbian, Gay, Bisexual or Transgender (LGBT) and being religious. This contradiction creates internal conflicts for many LGBT individuals.
Roni Roni
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Cross-cultural non-work transition stresses: domestic transferees in Indonesia
Purpose - The purpose of this paper is to address this gap in the literature by examining a cohort of Indonesians employed within a financial organisation and the cross-cultural transition stresses that they and their families encountered when relocated ...
Ratnasari, Sri Wahyuni, Hutchings, Kate
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Altertümliche Termini der rumänischen Viehzucht slavischer Herkunft
Archaic Animal Husbandry Terminology of Slavic Origin in the Romanian Language This article analyses a number of Romanian dialectal words and expressions associated with: (1) coat colours of farm animals, like ‘black’, ‘pied’, ‘spotted white’, ‘piebald’
Corinna Leschber
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Levels of Analysis in Cross-Cultural Psychology [PDF]
Cross-cultural psychologists seek to understand the nature of culture, a concept that can only be understood at the collective, supra-individual level. In most areas of psychology, researchers treat each individual as a separate source of data.
Peter B Smith (10014665) +2 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

