Results 51 to 60 of about 11,590,913 (256)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Ethno-Cultural Education in the Republic of Kalmykia: Is Civil Identity Formation in Danger?

open access: yesOriental Studies, 2018
The article examines the issues of ethno-cultural education in the Republic of Kalmykia within the general framework of maintaining balance between the all-Russian and ethnic identities.
G. S. Denisova   +2 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Unfamiliar Allies: Australian Cross-Cultural Communication in Afghanistan and Iraq During the War on Terror [PDF]

open access: yes, 2019
This chapter explores the social history of Australian military communication with their United States and Dutch allies in Afghanistan and Iraq. In spite of a long history of military association with the United States, challenges emerged both from the ...
Gehrmann, Richard, Richard Gehrmann
core   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Cross-cultural pragmatic failure and the esl classroom [PDF]

open access: yes, 1988
Language learning does not only involve the mastery of grammatical rules, it also includes the acquisition of the ability to use and understand language in context. This paper looks at pragmatic competence in second language teaching and learning. In the
Thiba, Tumelontle
core  

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Attitudes towards shoplifting: a preliminary cross-cultural study of consumers [PDF]

open access: yes, 2013
Shoplifting has a substantial impact on retailers, consumers and wider society, yet we know very little about people‟s attitudes towards this behaviour, especially from a non-Western perspective.
Whysall, P   +7 more
core  

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