Results 41 to 50 of about 1,092,301 (265)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Computational study of cross-flow in entropy-optimized nanofluids

Nanotechnology Reviews
Nanofluids (NFDs) are becoming better understood as a result of substantial boost in thermal efficiency advances and the rate of energy exchange employed in requisite fuel dynamics and automotive coolants. Owing to its usage, computational scrutinization
Li Shuguang, Abdullah Nermeen, Khan Umair, Zaib Aurang, Elattar Samia, Ishak Anuar   +5 more
doaj   +1 more source

China public emotion analysis under normalization of COVID-19 epidemic: Using Sina Weibo

Frontiers in Psychology, 2023
The prevention and control of the coronavirus disease 2019 (COVID-19) epidemic in China has entered a phase of normalization. The basis for evaluating and improving public health strategies is understanding the emotions and concerns of the public.
Fa Zhang, Fa Zhang, Qian Tang, Jian Chen, Na Han   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

CFD Simulation of Cross-Flow Filtration

Chemical Engineering Transactions, 2018
The aim of the present work is to study the transfer processes in a cross-flow filtration cell, in order to determine the conditions for stable and efficient operation of a side-stream filtration module, integrated with a bioreactor. The current interest in membrane integrated bioreactors is connected with the pursuit of energy and cost efficiency in a
Dzhonova-Atanasova Daniela B., Tsibranska Iren H., Paniovska Stela P.   +2 more
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Thermal Performance Improvement of Cross-Flow Double-Layered Microchannel Heat Sinks through Proper Header Design

Energies
Over the past two decades, double-layered microchannel heat sinks (DL-MCHs) have become increasingly popular as they provide effective performance for electronic cooling, particularly in the counterflow configuration.
Stefano Savino, Carlo Nonino
doaj   +1 more source

Cross flow water turbines: HARVEST technology

Renewable Energy and Environmental Sustainability, 2016
This paper describes all the main features of the hydrokinetic devices developed during the HARVEST program. Such devices, which eliminate the well-known weaknesses of Darrieus turbines, are composed of two counter-rotating twin columns of cross flow ...
Achard Jean-Luc, Dominguez Favio, Corre Christophe   +2 more
doaj   +1 more source

Impingement Cooling Characteristics of a Cube in Cross Flow [PDF]

Engineering and Technology Journal, 2009
An experimental and numerical investigation is carried out for the heat transfer froma cube faces subjected to impinging jet which centrally strikes the top face of the cube.
Jalal M. Jalil, Sabah T. Ahmed, Adnan A. Abdel Rasool   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source