Results 41 to 50 of about 543,959 (260)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Growth of Anabaena strains (Cyanophyceae) exposed to crossed gradients of light and temperature

Cryptogamie. Algologie, 1984
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Stulp, B K, Boele-Bos, S. A. (Stella S.), Stenveld, H, Stam, W T   +3 more
openaire   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Boosting Multitask Decomposition: Directness, Sequentiality, Subsampling, Cross-Gradients

sponsorship: This study was supported by the Hungarian National Research, Development, and Innovation Office K 139330 grant; the European Union (EU) Joint Program on Neurodegenerative Disease (JPND) Grant SOLID JPND2021-650-233; the National Research, Development, and Innovation Fund of Hungary under Grant TKP2021-EGA-02, the European Union project RRF-
Millinghoffer, Andras, Antal, Matyas, Marosi, Mark, Formanek, Andras, Antos, Andras, Antal, Peter   +5 more
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Buckling analysis of nonuniform nonlocal strain gradient beams using generalized differential quadrature method

Alexandria Engineering Journal, 2018
Recently, it was shown that the length scales presented in nonlocal elasticity and strain gradient theory each describe a different physical and material properties of structures at small scales.
H. Bakhshi Khaniki, Sh. Hosseini-Hashemi, A. Nezamabadi   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Quantifying the Drivers of Vegetation Resilience Gradient Effects Across Hierarchical Administrative Borders: A Case Study of the Beijing–Tianjin–Hebei Region

Land
Understanding vegetation resilience gradient effects across hierarchical administrative borders is critical for cross-jurisdictional land management yet remains underexplored.
Lifu Zheng, Yunlu Zhang, Ruojing Li, Kaiping Wang, Siqi Wu, Tieyue Qiang, Luxuan Lei   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source